L. R. M. Nhamo

Mechanisms of Phorbol Ester Toxicity, Determined by Molecular Modelling

A. Wakandigara, L. R. M. Nhamo, J. Kugara & P. Mushonga · International Research Journal of Pure and Applied Chemistry · 2020

Phorbol esters are toxic phytochemicals, whose main biological target is protein kinase C. They bind irreversibly to the protein, causing cell damage. Using computer modelling, we have determined, for the first time, features and mechanisms that lead to the toxicity of phorbol es...

Open access Research Article 10.9734/irjpac/2020/v21i1830267

Determination of Nitrogen and Sulphur Oxides Produced During Combustion of the Jatropha Cake as a Measure of the Level of Pollution When the Cake is Used as a Fuel

S. Mbera, L. R. M. Nhamo & T. Nyakungu · International Research Journal of Pure and Applied Chemistry · 2014

Jatropha cake is a promising renewable energy source after proving difficult to be used as feedstock. Its possible use as a combustible fuel makes the Jatropha cake pellet important as a source of potentially harmful gases to the users and the environment. This makes it imperativ...

Open access Research Article 10.9734/IRJPAC/2015/12889

Chemistry of Phorbol Ester Toxicity in Jatropha curcas Seed – a Review

A. Wakandigara, L. R. M. Nhamo & J. Kugara · International Journal of Biochemistry Research & Review · 2013

The toxicity of Jatropha curcas seeds emanates mainly from phorbol esters. It is known that the seeds are a valuable source of oil, which can be used to produce biodiesel. The cake generated as a by-product, after oil pressing is a protein-rich potential stock for animal feed. Re...

Open access Research Article 10.9734/IJBCRR/2013/2956