Assessing the Association between the Methylenetetrahydrofolate Reductase (MTHFR) 677C->T Polymorphism on Blood Folate Concentrations: A Systematic Review and Meta-analysis of Trials and Observational Studies
Becky Tsang, Amy Cordero, Claire Marchetta, Joseph Mulinare, Patricia Mersereau, Jing Guo, Yan Ping Qi, R. J. Berry, Jorge Rosenthal & Krista Crider · European Journal of Nutrition & Food Safety · 2015
Objectives: The methylenetetrahydrofolate reductase (MTHFR) 677C->T polymorphism is a risk factor for neural tube birth defects (NTDs). The T allele produces an enzyme with reduced folate processing capacity, which has been shown to produce lower blood folate concentrations in...
Open access
Research Article
10.9734/EJNFS/2015/21011