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Koichi Akashi

Publications (6)

Erythrocyte Membrane and Plasma Fatty Acids Composition in Patients with Coronary Heart Disease Requiring Percutaneous Angioplasty

Takeshi Arita, Taku Yokoyama, Mitsuhiro Fukata, Toru Maruyama, Seira Hazeyama, Shiro Mawatari, Takehiko Fujino & Koichi Akashi · Cardiology and Angiology: An International Journal · 2020

Aims: Atherosclerosis is associated with oxidative stress and fatty acid composition plays a critical role in vascular endothelial dysfunction and injury leading to the coronary atherosclerotic progression. However, the correlation between the fatty acid profile and coronary athe...

Open access Research Article 10.9734/ca/2020/v9i230132

Impairment of Erythrocyte Deformability Observed in Type 2 Diabetic Patients with Clustering Diabetic Complications

Takeshi Arita, Taku Yokoyama, Shohei Moriyama, Mitsuhiro Fukata, Kei Irie, Toru Maruyama, Takehiko Fujino & Koichi Akashi · Cardiology and Angiology: An International Journal · 2020

Aims: Hemorheologic and microvascular dysfunction are interdependent in type 2 diabetic patients. However, exact mechanisms explaining this interaction remains unclear. This study aimed to investigate the impairment of erythrocyte deformability under concurrent recording of elect...

Open access Research Article 10.9734/ca/2020/v9i130127

Vectorcardiographic Investigation of Brugada ECG Unmasked by Recording at Higher Intercostal Space

Takeshi Arita, Shioto Yasuda, Taku Yokoyama, Shohei Moriyama, Kei Irie, Mitsuhiro Fukata, Keita Odashiro, Toru Maruyama & Koichi Akashi · Cardiology and Angiology: An International Journal · 2018

Aims: Brugada syndrome is characterised by ST segment elevation in right precordial leads and associated sometimes with idiopathic ventricular fibrillation leading to sudden cardiac death. Although ECG recording at higher intercostal space unmasks Brugada syndrome, the vectorcard...

Open access Research Article 10.9734/CA/2018/45362

Serum Polyunsaturated Fatty Acid Profile and Carotid Intima-media Thickness in Japanese Atherosclerotic Patients Hospitalized for Endovascular Therapy

Hisataka Nakamura, Keita Odashiro, Masahiko Fujihara, Mitsuhiro Fukata, Takeshi Arita, Taku Yokoyama, Shioto Yasuda, Toru Maruyama & Koichi Akashi · Cardiology and Angiology: An International Journal · 2016

Aims: Serum eicosapentaenoic acid (EPA) to arachidonic acid (AA) ratio (EPA/AA) in Japanese is rapidly changing according to the senescence and food westernization, and sonographic carotid artery intima-media thickness (IMT) is increasingly used as a surrogate of systemic atheros...

Open access Research Article 10.9734/CA/2016/26017

Comparison of Human Erythrocyte Filterability with Trapping Rate Obtained by Nickel Mesh Filtration Technique: Two Independent Parameters of Erythrocyte Deformability

Takeshi Arita, Mitsuhiro Fukata, Toru Maruyama, Keita Odashiro, Takehiko Fujino, Chizuko Wakana, Aya Sato, Kazue Takahashi, Yoshiko Iida, Shiro Mawatari & Koichi Akashi · International Blood Research & Reviews · 2018

Background: Erythrocyte deformability is a major determinant of microcirculation in vivo. Although this concept was defined as filterability evaluated by flow-pressure curve constructed during a filtration process of erythrocyte suspension through a nickel mesh filter, the behavi...

Open access Research Article 10.9734/IBRR/2018/44667

Plasma and Erythrocyte Membrane Plasmalogens in Patients with Coronary Heart Diseases Undergoing Percutaneous Intervention

Takeshi Arita, Taku Yokoyama, Shohei Moriyama, Kei Irie, Mitsuhiro Fukata, Keita Odashiro, Toru Maruyama, Seira Hazeyama, Shiro Mawatari, Takehiko Fujino & Koichi Akashi · Cardiology and Angiology: An International Journal · 2018

Aims: Plasmalogens are unique phospholipid of biological membrane and is considered to play a potent role of intrinsic antioxidant. Atherosclerosis is associated with oxidative stress, but the correlation between plasmalogens and atherosclerosis is debatable. Therefore, this stud...

Open access Research Article 10.9734/CA/2018/44602