Kerolayne de Melo Nogueira

Mechanisms Underlying Weight Regain After GLP-1RA Treatment: A Neurobiological Perspective

Kerolayne de Melo Nogueira & Ian Jhemes Oliveira Sousa · Annual Research & Review in Biology · 2026

Weight rebound after discontinuation of GLP-1 receptor agonists (GLP-1RAs) is common and often misinterpreted as a sign of weak willpower. This review summarizes preclinical and clinical evidence on how GLP-1RAs affect food stimulus processing and other systems that determine rel...

Open access Research Article 10.9734/arrb/2026/v41i12370

Design and In silico Validation of Primers for Assessing Gene Expression in the Canonical Inflammatory Pathway

Ian Jhemes Oliveira Sousa, Kerolayne de Melo Nogueira, Higo José Neri da Silva & Ester Miranda Pereira · Advances in Research · 2025

Aims: This study aimed to design and validate primers to investigate the expression of key genes of the canonical inflammation pathway, specifically NEMO (NF-kappaB Essential Modulator), MyD88 and IL-1β, in order to ensure feasibility, specificity and efficiency for use in RT-qPC...

Open access Research Article 10.9734/air/2025/v26i11265