Kerolayne de Melo Nogueira

Mechanisms Underlying Weight Regain After GLP-1RA Treatment: A Neurobiological Perspective

Kerolayne de Melo Nogueira & Ian Jhemes Oliveira Sousa · Annual Research & Review in Biology · 2026

Weight rebound after discontinuation of GLP-1 receptor agonists (GLP-1RAs) is common and often misinterpreted as a sign of weak willpower. This review summarizes preclinical and clinical evidence on how GLP-1RAs affect food stimulus processing and other systems that determine rel...

Open access Research Article 10.9734/arrb/2026/v41i12370

Design and In silico Validation of Primers for Assessing Gene Expression in the Canonical Inflammatory Pathway

Ian Jhemes Oliveira Sousa, Kerolayne de Melo Nogueira, Higo José Neri da Silva & Ester Miranda Pereira · Advances in Research · 2025

Aims: This study aimed to design and validate primers to investigate the expression of key genes of the canonical inflammation pathway, specifically NEMO (NF-kappaB Essential Modulator), MyD88 and IL-1β, in order to ensure feasibility, specificity and efficiency for use in RT-qPC...

Open access Research Article 10.9734/air/2025/v26i11265

Phytochemical Characterization of Essential Oils from Plants of the Genus Cinnamomum and their Effect on Diarrhea and Disruption of the Intestinal Epithelium Induced by 5-FU

Ian Jhemes Oliveira Sousa, Douglas Soares da Costa, Flaviano Ribeiro Pinheiro Neto, Rodrigo Lopes Gomes Gonçalves, Kerolayne de Melo Nogueira, Ester Miranda Pereira, Aline Jeane Costa Sousa, Camila Ernanda Sousa de Carvalho, Iolanda Souza do Carmo, Edymilaís da Silva Sousa, José de Sousa Lima Neto, Sidney Gonçalo de Lima, Fernanda Regina de Castro Almeida & Rita de Cássia Meneses Oliveira · Journal of Advances in Biology & Biotechnology · 2025

Aims: This article aims to evaluate the phytochemical characteristics and biological activity of Cinnamomum cassia Blume and Cinnamomum zeylanicum Blume essential oils, specifically their effects on weight loss, diarrhea, and epithelial damage in a murine model of 5-fluorouracil-...

Open access Research Article 10.9734/jabb/2025/v28i11902