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Joko Wibowo Sentoso

Publications (13)

Laser and Plasma-based Technologies for Precision Tumor Ablation: A Narrative Review

Joko Wibowo Sentoso, Henky Agung Nugroho, Darmawan Ismail & Suryo Wahyu Raharjo · Journal of Cancer and Tumor International · 2025

The pursuit of precision in oncologic surgery remains a critical challenge, as conventional resection techniques often face limitations in achieving tumour-free margins while minimising collateral tissue damage. In recent years, energy-based surgical modalities such as laser and...

Open access Research Article 10.9734/jcti/2025/v15i4320

Comparison of Intravenous and Topical Injection Administration Mesenchymal Stem Cell Secretome to Restrain Gastrointestinal Anastomosis Leakage: A Review

Joko Wibowo Sentoso, Agung Putra, Ida Bagus Budhi SA, Anung Noto Nugroho & Suryo Wahyu Raharjo · International Research Journal of Gastroenterology and Hepatology · 2025

Intestinal anastomosis is one of the most commonly performed gastrointestinal surgical procedures, especially in emergencies and is commonly performed in elective procedures when resection is performed for benign or malignant lesions of the gastrointestinal tract. One of the impo...

Open access Research Article 10.9734/irjgh/2025/v8i1107

The Role of MSC-Derived Exosomes in Soft Tissue Remodelling via the PTEN and PI3K/AKT Pathway Following Wide Excision of Fibrosarcoma: A Review

Joko Wibowo Sentoso, Agung Putra, Iffan Alif & Henky Agung Nugroho · Asian Journal of Medicine and Health · 2025

Fibrosarcoma is a neoplasm of fibroblast tissue with varying collagen production. Fibrosarcoma, an aggressive form of soft tissue cancer, is currently a major challenge in the field of oncology. Although its prevalence is relatively low compared to other cancers, fibrosarcoma's s...

Open access Research Article 10.9734/ajmah/2025/v23i11156

The Role of Mesenchymal Stem Cells Secretome in Regeneration of Thyroid Tissue Damage after Thyroid Lobectomy: A Literature Review

Joko Wibowo Sentoso, Agung Putra & Henky Agung Nugroho · Journal of Cancer and Tumor International · 2024

Mesenchymal Stem Cells (MSC) are a type of stem cell that is multipotent and originates from the mesoderm and ectoderm at an early stage of development and can differentiate into: 1. Ectodermal derivatives such as: neurons, keratocytes and keratinocytes; 2. Endodermal derivatives...

Open access Research Article 10.9734/jcti/2024/v14i2252

Optimization of PD-1 / PD-L1 Blockade to Increase NK Cells Cytotoxicity in Killing Cancer Cells: Article Review

Joko Wibowo Sentoso, Agung Putra & Iffan Alif · Journal of Cancer and Tumor International · 2024

Anti-PD-1 and anti-PD-L1 are therapies that have shown success in cancer treatment. However, while treating cancer with PD-1/PD-L1 blockade is similar, the clinical response rate is still low in certain cancers at around 40%. Therefore, therapeutic strategies are needed to increa...

Open access Research Article 10.9734/jcti/2024/v14i1248

Targeting Unique Features of Quiescent Cancer Stem Cells to Overcome Resistance and Recurrence in Cancer Therapy: A Review

Joko Wibowo Sentoso, Agung Putra & Iffan Alif · Journal of Cancer and Tumor International · 2024

Quiescent cancer stem cells (QCSC) are non-proliferating cells that survive in the G0 phase and have low ki-67 expression and high p27 expression. QCSCs have the ability to evade most chemotherapy, and some subsequent treatments may result in a higher proportion of quiescent canc...

Open access Research Article 10.9734/jcti/2024/v14i1247

Comparison of Long-term Outcomes between Hirschsprung's Disease Patients after Soave Procedure and Duhamel Procedure Based on the Paediatric Incontinence and Constipation Scoring System: A Retrospective Cohort Study

Joko Wibowo Sentoso, Nunik Agustriani & Ida Bagus Budhi SA · Asian Journal of Medicine and Health · 2024

Introduction: Hirschprung's disease is a congenital disease that causes intestinal motility disorders. Hirschprung's disease is still the most common condition that causes intestinal obstruction in children. The incidence of Hirschprung's disease is 1:5000 live births. The incide...

Open access Research Article 10.9734/ajmah/2024/v22i51011

Apoptotic Effects of Adipose-Derived Stem Cell Secretome in Breast Cancer Stem Cells: A Literature Review

Joko Wibowo Sentoso, Agung Putra & Iffan Alif · Journal of Cancer and Tumor International · 2024

Adipose-derived stem cells (ASC) are cells from the core of fat tissue that secrete various cytokines, growth factors, proteins and extracellular vesicles that can be used in regenerative therapy, especially in the case of cancer. This ASC produces a secretome which is an exosome...

Open access Research Article 10.9734/jcti/2024/v14i1244

Management of Nodular Nasal Basal Cell Carcinoma with Wide Excision, Transpositional Median Forehead Flap, Forehead Split Thickness Skin Graft: Case Report

Joko Wibowo Sentoso, Henky Agung Nugroho & Affandi Wiramur · Journal of Cancer and Tumor International · 2023

Introduction: Basal cell carcinoma (BCC) is the most common skin type cancer with an incidence rate of around 75-80%. The most common location is in the head and neck area around 70-80% and followed by other body parts around 25% consist of the penis, vulva or perianal area and 5...

Open access Research Article 10.9734/jcti/2023/v13i3-4243

The Role of Adipose-derived Stem Cell in Breast Reconstruction with Fat Grafting: A Literature Review

Joko Wibowo Sentoso, Agung Putra & Iffan Alif · Journal of Cancer and Tumor International · 2023

Adipose-derived stem cells (ADSC) are a biological development that provides new hope regarding tissue engineering and regenerative therapy. Due to its potential paracrine activity, compounding, paracrine activity and immunomodulatory function, ADSC-based cell-assisted lipotransf...

Open access Research Article 10.9734/jcti/2023/v13i3-4245

Giant Multicyst Neck Lymphangioma in Adult with Single Session Ethanol Ablation Treatment: Rare Case Report

Joko Wibowo Sentoso & Kristanto Yuli Yarsa · Journal of Cancer and Tumor International · 2023

Introduction: Neck lymphangioma is a benign congenital malformation that occurs frequently in children, and is rare in adults. They are usually found in the head and neck region and are often considered a metastatic lesion rather than a primary neoplasia. Most lymphangiomas are a...

Open access Research Article 10.9734/jcti/2023/v13i3239

Anterior Thigh Myxofibrosarcoma with Management of Wide Excision and Modified Anterior Thigh Compartment Resection : A Case Report

Joko Wibowo Sentoso & Kristanto Yuli Yarsa · Journal of Cancer and Tumor International · 2023

Introduction: Myxofibrosarcoma (MFS) is a type of malignancy from the group of malignant fibrous histiocytoma. Myfxofibrosarcoma is a type of soft tissue neoplasm that is aggressive. The clinical symptoms are not pathognomonic and the histological picture is very heterogeneous, o...

Open access Research Article 10.9734/jcti/2023/v13i3238

Oral Squamous Cell Carcinoma of the Mandible with Management of Wide Excision, Right Hemimandibulectomy, Mandibular Reconstruction, and Pectoralis Major Myocutaneus Flap: A Rare Case Report

Joko Wibowo Sentoso & Widyanti Soewoto · Journal of Cancer and Tumor International · 2023

Aims: To report the case of a man diagnosed with mandibular mucogingival SCC and present its case details, histopathological findings, and management. Presentation of Case: A 35-year-old man with complaints of lumps and a wound on the right side of the face that has been getting...

Open access Research Article 10.9734/jcti/2023/v13i2232