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Jacob A. Akpan

Publications (2)

Technology-assisted Neurobehavioral and Histomorphometric Assessment of Chronic Lead and Cadmium Exposure in an Animal Study

Ndubuisi F. Nwodo, Charles C. Nwafor, Okafor K. Oluchi, Ifedi I. Charles, Jacob A. Akpan & Felix O. Ogbo · Biotechnology Journal International · 2026

Backgrounds: Heavy metals like lead (Pb) and cadmium (Cd) are toxic environmental pollutants that cause serious health effects, particularly neurotoxicity, organ damage, and carcinogenic risks. Their combined exposure can enhance toxicity through synergistic interactions, increas...

Open access Research Article 10.9734/bji/2026/v30i2867

Biochemical Modulation of Streptozotocin Neurotoxicity by Cinnamonum Verum Bark Extract in Wistar Rats

Ifedi I. Charles, Nwafor C. Charles, Ojimba M. Immaculata, Okeke J. Chioma & Jacob A. Akpan · European Journal of Medicinal Plants · 2025

This study investigates the effects of Cinnamomum verum bark extract on Streptozotocin (STZ) induced neurotoxicity in Wistar rats. Twenty five (25) Male Wistar rats weighing between 93.4 -107.6g were divided into five groups: Group A: Control, Group B 65mg/kg STZ, Group C 65mg/kg...

Open access Research Article 10.9734/ejmp/2025/v36i21250