Effect of Carboplatin and Methotrexate on Lipid Levels in the Plasma Membrane of MCF-7 Cells and their Association with Cell Motility
J. Borjac, R. Dannaoui, H. Saab, M. Dakdouki, M. El-Sibai & J. Usta · International Journal of Biochemistry Research & Review · 2015
Aim: We examine in this study the effect of two antitumor drugs metothrexate (MTX) and carboplatin (CPT) on the phospholipid content of plasma membrane of MCF-7 breast cancer cells. MTX is a folate analog that inhibit dihydrofolate reductase. CPT is a platinum-containing antineop...
Open access
Research Article
10.9734/IJBCRR/2015/20709