Aim: The work was designed to investigate the antmalarial activity of methanolic leaf extract of Carica papaya on Plasmodium berghei NK65 strain infection in vivo. Place and Duration of Study: Department of Biochemistry and National Institute of Pharmaceutical Research and Develo...
Open access
Research Article10.9734/EJMP/2017/34698
Aim: Interest in phospholipase A2 has continued to rise since its biotechnological potentials and involvement in the pathogenicity of Trypanosoma species were recognized, therefore this study was designed to investigate the vaccine potential of Trypanosoma brucei PLA2 gene contai...
Open access
Research Article10.9734/AJMAH/2016/30065
Aim: This work focused on the sequence homology studies of the enzyme, phospholipase A2 (PLA2), in Trypanosoma brucei obtained from the blood of bull in Federe, Plateau State, Nigeria, West Africa Place and Duration of Study: Department of Biochemistry, University of Jos, Nige...
Open access
Research Article10.9734/BBJ/2015/13971
Diabetes mellitus is a disease associated with the increase in Blood glucose level caused by the abnormalities of glucose receptors in the uptake of glucose or total destruction of the β pancreatic cell, with approximately 366 millions of people worldwide diagnosed with the disea...
Open access
Research Article10.9734/EJMP/2017/34702
Aim: The study explored the diversity of Plasmodium falciparum Merozoite Surface Protein 1 (msp-1) gene sequence and delineated the K1 allele occurrence and profile. The Plasmodium falciparum msp-1 gene encodes an antigen that is being proposed as a major vaccine candidate agains...
Open access
Research Article10.9734/ijpr/2023/v12i6260
Aim: This research work investigated the impact of the differences in duration of alcoholic beverage consumption on hepatic and heamatological parameters. Methods: Fifty (50) healthy male volunteer subjects were recruited for this study from Kadima district of Jos South Local Gov...
Open access
Research Article10.9734/jalsi/2021/v24i530236
Kakjing D. Falang, Catherine O. Poyi, Ukpe Ajima, Bukata B. Bukar, Kennedy I. Amagon, James G. Damen, Yusuf Agabi, Richard J. Kutshik, Ishaya Y. Longdet, Simji S. Gomerep, Ismaila Shittu, Stephen D. Davou, Jacob A. Kolawole & Noel N. Wannang·Journal of Complementary and Alternative Medical Research·2020
The coronavirus disease COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) has presented unprecedented challenges to the healthcare systems in the world. There are no definite effective therapeutic agents or vaccines against the virus currentl...
Open access
Research Article10.9734/jocamr/2020/v12i130199
Nelson J. Nwankwo, Joel Paul, Shangshikmwa K. Gaknung, Timloh Fakdul, Mercy O. Simon, Dinci T. Davou, Mary M. Mankilik, Richard J. Kutshik, Bitrus Yakubu & Ishaya Y. Longdet·Asian Journal of Biotechnology and Genetic Engineering·2024
Aim: This study investigates mutations at codon 540 in the dihydropteroate synthetase (540dhps) gene that may confer resistance to sulfadoxine-pyrimethamine treatment by Plasmodium falciparum in Jos. Study Design: The research employs a cross-sectional study design. Place and Dur...
Joel Paul, Nelson J. Nwankwo, Mercy O. Simon, Shangshikmwa K. Gaknung, Timloh Fakdul, Dinci T. Davou, Mary M. Mankilik, Richard J. Kutshik, Bitrus Yakubu & Ishaya Y. Longdet·Journal of Advances in Biology & Biotechnology·2023
Aim: The aim of this study was to explore the Plasmodium falciparum Artemisinin Resistant Gene (Pfkelch13) in malaria cases in Jos and profile the nature of the mutations. The Plasmodium falciparum kelch13 gene is a potential molecular marker for tracking artemisinin-resistant ma...
Open access
Research Article10.9734/jabb/2023/v26i10661
Timloh Fakdul, Shangshikmwa K. Gaknung, Mercy O. Simon, Nelson J. Nwankwo, Joel Paul, Hafsat S. Jagab, Daniel G. ThankGod, Dinci T. Davou, Mary M. Mankilik, Richard J. Kutshik, Bitrus Yakubu & Ishaya Y. Longdet·Asian Journal of Research in Biochemistry·2024
Background: Malaria remains a significant health threat globally, with Plasmodium falciparum being the predominant and lethal parasite in Africa. Nigeria is still faced with ongoing cases of asymptomatic malaria, hindering effective control measures. Aim: The aim was to generate...
Open access
Research Article10.9734/ajrb/2024/v14i1273