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Ifeoma N. Nweke

Publications (9)

Weight Gain Reduction and Hypoglycemic Effects of Xylopia aethiopica Fruit Extract on Wistar Rats

Emmanuel O. Ogbuagu, Ifeoma N. Nweke, Prince C. Unekwe, Augustine I. Airaodion & Uloaku Ogbuagu · International Journal of Research and Reports in Hematology · 2021

Aim: This study is aimed at determining the effect of Xylopia aethiopica fruit on weight gain and blood sugar level of Wistar rats. Methodology: The fruits of Xylopia aethiopica were obtained from new market in Aba, Abia State, Nigeria and were authenticated. They were air-dried...

Open access Research Article

Hepatotoxic effect of Xylopia aethiopica Fruit in Wistar Rats

Emmanuel O. Ogbuagu, Prince C. Unekwe, Augustine I. Airaodion, Ifeoma N. Nweke & Uloaku Ogbuagu · International Research Journal of Gastroenterology and Hepatology · 2021

Background: Xylopia aethiopica fruit has been reported to possess high medicinal value. Thus, people use it without any regard for its toxicity. Aim: This study is therefore aimed at investigating its toxicity on the liver of Wistar rats. Methodology: The fruits of Xylopia aethio...

Open access Research Article

Nephrotoxicity of Ethanol Extract of Xylopia aethiopica Fruit in Wistar Rats

Emmanuel O. Ogbuagu, Augustine I. Airaodion, Uloaku Ogbuagu, Ifeoma N. Nweke & Prince C. Unekwe · International Journal of Advances in Nephrology Research · 2021

Background: The use of Xylopia aethiopica fruit in folklore medicine is on the increase without regard to its toxicity. Aim: This study was aimed at examining its toxicity on the kidney of Wistar rats. Methodology: The fruits of Xylopia aethiopica were air-dried and extracted usi...

Open access Research Article

Hypolipidemic Propensity of Ethanolic Extract of Xylopia aethiopica Fruit in Wistar Rats

Emmanuel O. Ogbuagu, Prince C. Unekwe, Augustine I. Airaodion, Ifeoma N. Nweke & Uloaku Ogbuagu · Asian Journal of Research in Cardiovascular Diseases · 2021

Aim: This study is aimed at assessing the effect of Xylopia aethiopica fruit on the lipid profile of Wistar rats. Methodology: The fruits of Xylopia aethiopica were obtained from new market in Aba, Abia State, Nigeria and were authenticated. They were air-dried and extracted usin...

Open access Research Article

Qualitative Determination of the Phytochemical Composition of Ethanolic Extract of Xylopia aethiopica Fruit

Emmanuel O. Ogbuagu, Uloaku Ogbuagu, Prince C. Unekwe, Ifeoma N. Nweke & Augustine I. Airaodion · Asian Journal of Medical Principles and Clinical Practice · 2020

Aim: The aim of this study is to qualitatively determine the phytochemical compositions of ethanolic extract of Xylopia aethiopica fruit. Methodology: The fruits of Xylopia aethiopica were obtained from new market in Aba, Abia State and were identified and authenticated by Prof....

Open access Research Article

Ethanolic Extract of Xylopia aethiopica (African Negro Pepper) Fruit Adversely Perturbed Semen Qualities in Male Wistar Rats

Emmanuel O. Ogbuagu, Augustine I. Airaodion, Uloaku Ogbuagu, Edmund O. Ezirim, Ifeoma N. Nweke & Prince C. Unekwe · International Journal of Research and Reports in Gynaecology · 2022

Aim: This study was designed to assess the effect of Xylopia aethiopica fruit on the sperm qualities of male Wistar rats. Methodology: The fruits of Xylopia aethiopica were air-dried and extracted by Soxhlet extractor using ethanolic as solvent. The median lethal dose (LD50) of t...

Open access Research Article

Alterations in Female Reproductive Hormones of Wistar Rats Sequel to the Administration of Xylopia aethiopica Fruit

Emmanuel O. Ogbuagu, Augustine I. Airaodion, Chika L. Uche, Uloaku Ogbuagu, Edmund O. Ezirim, Ifeoma N. Nweke & Prince C. Unekwe · Asian Research Journal of Gynaecology and Obstetrics · 2022

Aim: This present study was designed to examine the impact of Xylopia aethiopica fruit on the reproductive hormones of female Wistar rats. Methodology: The fruits of Xylopia aethiopica were air-dried and extracted by Soxhlet extractor using ethanol as solvent. The lethal dose of...

Open access Research Article

Effect of Ethanol Extract of Xylopia aethiopica Fruit on Oxidative Stress Indices of Wistar Rats

Emmanuel O. Ogbuagu, Uloaku Ogbuagu, Augustine I. Airaodion, Chika L. Uche, Edmund O. Ezirim, Ifeoma N. Nweke & Prince C. Unekwe · Asian Journal of Immunology · 2022

Background: The use of Xylopia aethiopica fruit in folklore medicine is on the increase without caution of its toxicity. Aim: This present study tends to assess its effect on the oxidative stress biomarkers of Wistar rats. Methodology: The fruits of Xylopia aethiopica were air-dr...

Open access Research Article

Xylopia aethiopica Fruit Increased Prothrombin Time, Activated Partial Thromboplastin Time and Erythrocyte Sedimentation Rate of Wistar Rats

Emmanuel O. Ogbuagu, Augustine I. Airaodion, Chika L. Uche, Uloaku Ogbuagu, Edmund O. Ezirim, Prince C. Unekwe & Ifeoma N. Nweke · International Journal of Research and Reports in Hematology · 2022

Background: Traditionally, the use of Xylopia aethiopica fruit for therapeutic purposes is on the increase without any consideration of its safety and toxicity. Aim: This study was therefore designed to examine its effect on coagulation factors of Wistar rats. Methodology: The fr...

Open access Research Article