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Henry I. C. Lowe

Publications (6)

Anticancer Activity of Three Jamaican Macroalgae against Prostate, Pancreatic and Skin Cancers

Henry I. C. Lowe, Denise Daley, Charah Watson, Shelly-Ann Powell, Kenneth N. N. Ayeah, Ngeh J. Toyang, Joseph Bryant & Andrew S. Lamm · European Journal of Medicinal Plants · 2016

Aims: Cancer is one of the leading chronic diseases that may lead to death. The search for new therapeutic, medicinal and nutraceutical compounds from folkloric plants including the marine flora are globally important objectives. Therefore the biological assessment of macroalgae...

Open access Research Article 10.9734/EJMP/2016/23662

Inhibition of the Human Hepatitis C Virus by Dibenzyl Trisulfide from Petiveria alliacea L (Guinea Hen Weed)

Henry I. C. Lowe, Ngeh J. Toyang, Sanjit Roy, Charah T. Watson & Joseph L. Bryant · Microbiology Research Journal International · 2015

Aim: The anti cancer and anti diabetic properties of the extract from the P. alliacea a naturally occuring plant found in Jamaica, have been described previously but its role against hepatitis C virus (HCV) infection is completely unknown. The aim of the study was to evaluate the...

Open access Research Article 10.9734/BMRJ/2016/22120

Petiveria alliacea L (Guinea Hen Weed) and Its Major Metabolite Dibenzyl Trisulfide Demonstrate HIV-1 Reverse Transcriptase Inhibitory Activity

Henry I. C. Lowe, Ngeh J. Toyang, Alonso Heredia, Kenneth N. N. Ayeah, Charah T. Watson & Joseph Bryant · European Journal of Medicinal Plants · 2014

Aim: The human immunodeficiency virus (HIV) remains a major public health concern despite the discovery and development of Highly Active Antiretroviral Therapies (HAART). There is as such a need to continue to search for new and effective therapies for this global pandemic. In an...

Open access Research Article 10.9734/EJMP/2015/12064

Unearthing the Medicinal Properties of Tillandsia recurvata (Ball Moss): A Mini Review

Henry I. C. Lowe, Charah T. Watson, Simone Badal, Ngeh J. Toyang & Joseph Bryant · European Journal of Medicinal Plants · 2014

Background: More than half of traditional medicines are of natural origin and research has shown that these are associated with fewer side effects than the synthetic ones, since less than 10% of the 350,000 identified plant species have been exposed to some amount of bioactive sc...

Open access Research Article 10.9734/EJMP/2014/11028

Anti HIV-1 Activity of the Crude Extracts of Guaiacum officinale L. (Zygophyllaceae)

Henry I. C. Lowe, Ngeh J. Toyang, Alonso Heredia, Charah T. Watson & Joseph Bryant · European Journal of Medicinal Plants · 2014

Aim: Jamaica is rich in medicinal plants.  Guaiacum officinale is the “National Flower”, with reported uses in folk medicine for the treatment of various conditions including inflammation.  In our search for plants with anticancer and anti-infective properties, we evaluated Guaia...

Open access Research Article 10.9734/EJMP/2014/7343

Cycloartanes with Anticancer Activity Demonstrate Promising inhibition of the Mrckα and Mrckβ Kinases

Henry I. C. Lowe, Ngeh J. Toyang, Charah T. Watson & Joseph Bryant · Journal of Advances in Medicine and Medical Research · 2014

Aim: The role of Kinases in cancer onset and progression has made kinases a target for the control of some cancers. Recent discoveries that kinases are most effectively inhibited by small molecules have also resulted in an increased search for small molecule kinase inhibitors. Cy...

Open access Research Article 10.9734/BJMMR/2014/6877