Hassan S. Darwish

Exploring Gene Therapy Strategies for Cystic Fibrosis: A Comprehensive Review of CFTR Gene Mutations, Bioinformatics Analysis, and Emerging Therapeutic Approaches

Hassan S. Darwish, Hajer Almamri, Manohar Noone, Azher Alhabsi & Una Gibbons · Biotechnology Journal International · 2024

Aim: This study aimed to identify the most promising gene therapy approach for treating patients with cystic fibrosis. Background: Cystic fibrosis is a rare autosomal recessive disorder affecting malabsorption, malnutrition, and lung function. It results from genetic mutations in...

Open access Research Article 10.9734/bji/2024/v28i1713

Genomic Study of TCF7L2 Gene Mutation on Insulin Secretion for Type 2 DM Patients: A Review

Hassan S. Darwish, Badriya Alrahbi, Hajer Almamri, Manohar Noone, Hussam Osman & Ashgan Abdelhalim · Annual Research & Review in Biology · 2022

Aim: This paper aims to establish whether a correlation between TCF7L2 gene mutation on insulin secretion for Type 2 DM Patients. Background: Diabetes type 2 is the most common metabolic disorder worldwide. Beta cell dysfunction reduces insulin secretion and increases the glucose...

Open access Research Article 10.9734/arrb/2022/v37i1230560