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H. K. Okafor

Publications (5)

Antidiabetic and Hypolipidaemic Effects of Garden Egg (Solanum aethiopicum) Leaf Extract in Beta-cells of Streptozotocin Induced Diabetic Male Wistar Rats

H. K. Okafor, A. I. Odugbemi, C. B. Okezie & M. K. Achebe · Annual Research & Review in Biology · 2016

Aim: Diabetes and cardiovascular disorders have continued to pose serious threats to humans. Hence researches have been ongoing on discovery of more antidiabetic and hypolipidaemic plants. Therefore, this study evaluated the antidiabetic, hypolipidaemic and histopathological prof...

Open access Research Article 10.9734/ARRB/2016/26841

A Comparative Study of the Ameliorative Effects of Skimmed Milk and Tuna Fish in the Dietary Management of Dexamethasone Sodium Phosphate Induced Osteoporotic Female Wistar Rats

H. K. Okafor, A. I. Odugbemi & S. E. Omogo · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Objective: This investigation was carried out to compare the moderating effects of skimmed milk and whole dried Tuna fish in osteoporotic female rats. Methods: Sixty female albino Wistar rats were divided into two main groups. The first group (ten rats) fed basal diet and was mai...

Open access Research Article 10.9734/JAMPS/2016/24382

Influence of Active and Passive Smoking on the Urinary Concentration of 1 Hydroxyl Pyrene, Oxidative Stress and Renal Activity in Male Subjects

H. K. Okafor, S. E. Omogo & Y. A. Omoniyi · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Objective: The purpose of the study was to investigate the influence of active and passive smoking on the urinary concentration of 1 hydroxyl pyrene, oxidative stress and renal activity in male subjects. Methods: Urine samples each of forty active and passive smokers including fo...

Open access Research Article 10.9734/JAMPS/2016/23966

Defatted Soya Flour Supplementation of Wheat Bread Confers Oxidative, Renal, Hepatic and Cardiovascular Protective Effects in Wistar Rats

H. K. Okafor & O. A. T. Ebuehi · International Journal of Biochemistry Research & Review · 2016

Background: The present study was designed to ascertain the effect of supplementation of bread with defatted soy flour on antioxidant, renal, hepatic and cardiovascular status in Wistar rats. Methods: Hard wheat flour was mixed with high quality defatted soy flour at several rati...

Open access Research Article 10.9734/IJBCRR/2016/22912

Transdermal Drug Delivery: Microneedles, Their Fabrication and Current Trends in Delivery Methods

M. Ogundele & H. K. Okafor · Journal of Pharmaceutical Research International · 2017

The past few decades have seen a tremendous growth in the use of microneedles in the transdermal delivery of therapeutics. This is due to the several advantages that microneedles offer in the delivery of compounds. Therapeutics are delivered in a simple, minimally invasive and pa...

Open access Research Article 10.9734/JPRI/2017/36164