Gurunathan Ramalingam

Development and Validation of a Diethyl Phosphite Content in Foscarnet Sodium USP by GC MS Technique

Mohan Bhatale, Neelakandan Kaliyaperumal, Gopalakrishnan Mannathusamy & Gurunathan Ramalingam · Journal of Pharmaceutical Research International · 2021

A simple, rapid, selective, and reproducible Gas chromatographic mass spectrometry (GC-MS) method has been developed and validated for the estimation of Diethyl Phosphite content in Foscarnet Sodium USP Drug substance. The drugs were estimated using HP-5, Length-30 M, Internal di...

Open access Research Article 10.9734/jpri/2021/v33i46A32857

Development and Validation of Estimation of Genotoxic Impurity (Benzimidamidecontent) in Leflunomide by Using RP-HPLC Technique

Mohan Bhatale, Neelakandan Kaliyaperumal, Gopalakrishnan Mannathusamy & Gurunathan Ramalingam · Journal of Pharmaceutical Research International · 2021

The measurement of Genotoxic contaminant, a simple, selective, linear, accurate, and specific reverse phase high-performance liquid chromatographic (RP-HPLC) process was proposed. A Benzimidamide impurity in the medication Leflunomide has been discovered. Separation and analysis...

Open access Research Article 10.9734/jpri/2021/v33i45B32782