Interaction of Antimalarial Drug, Pyrimethamine and Sulphadoxine with Sickle Haemoglobin at pH 5.0 and pH 7.2: A Fourier Transform Infrared (FTIR) Study
A. E. Amalunweze, A. L. Ezugwu, S. O. O. Eze & F. C. Chilaka · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022
Aggregation of sickle haemoglobin (HbS), upon deoxygenation, is responsible for an inherited genetic disorder in the human red blood cells (RBCs) known as Sickle cell disease (SCD). On the suggestion that this phenomenon could arise from some form of conformational changes in the...
Open access
Research Article
10.9734/ajbgmb/2022/v10i230243