Plant growth regulators (PGRs) are compounds that regulate plant growth and development and are used in agriculture to enhance productivity and stress tolerance. Major classes include auxins, gibberellins, and cytokinins. However, improper use of PGRs can pose toxicological risks...
Open access
Research Article10.9734/ajrb/2026/v16i2483
Ehab Tousson, Afaf El-Atrash, Ibrahim El Tantawy El Sayed, Ezar Hafez, Hebat Allah El Basyouny & Ramadan M. Kandyel·Asian Oncology Research Journal·2021
Background and Objective: The study aims to evaluate the protective activity of 9-Diaminoacridine (N1-(acridin-9-yl) propane-1, 3-diamine hydrochloride; 9-DAAD) against Ehrlich Ascites Carcinoma (EAC) bearing mice. Materials and Methods: A total forty mice were randomly divided i...
Background and Objective: Monosodium glutamate (MSG) is identified as an Accent that is used in the food industry as a flavour enhancer with an umami taste that intensifies the meaty, savoury flavour of food. The present study aimed at evaluating the protective and ameliorative r...
Open access
Research Article10.9734/ajrimps/2019/v8i3-430136
Objectives: Ginkgo biloba leaf extract (GBLE) and L-carnitine extract are a commercial product used as a nutraceutic herbal widely. They have antioxidant and reactive oxygen species (ROS) scavenger. This study hypothesized that GB and L-carnitine may have protective effects again...
Open access
Research Article10.9734/arrb/2019/v32i230076
Background and Objective: Breast cancer is one of the most common cause of cancer deaths among women worldwide. Etoposide is an important chemotherapeutic agent that is used to treat a wide spectrum of human cancers. It has been in clinical use for more than two decades and remai...
Background and Objective: Breast cancer is the most common type of cancer among women and the second most frequent kind of tumor worldwide. This study aims to find the renal and hepatic protective effect of etoposide against Ehrlich solid tumor induced liver and kidney toxicity i...
Ehrlich model is mammary cancer it is passed via intraperitoneal passages from a mouse to another. Because of the ability of Ehrlich tumor to grow and spread rapidly after transplantation, it has been used in many experimental studies looking for a way to fight diseases and reduc...
Background and Objective: The present study aimed to examine the possible modifying effects of ginseng extract against both liver and kidney injuries induced by Cisplatin in rats. Materials and Methods: A total of 24 male albino rats were equally divided into six groups; the firs...
Aims: Cancer is caused by an imbalance in the rate of proliferation and apoptosis and the positive effect of anticancer therapy is taken into consideration when its ability to initiate apoptosis in cancer cells. In vivo; several experimental models established in experimental ani...
Aims: Depression is a mental health issue that starts most often in early adulthood and it is a common and recurrent disorder causing significant morbidity and mortality worldwide. Amitriptyline is a tricyclic antidepressant that is known to inhibit the presynaptic reuptake of se...
Open access
Research Article10.9734/ajrimps/2019/v7i430128
Objects: Amitriptyline is a widely used tricyclic antidepressant. Amitriptyline is well-known for its cardiovascular side effects and toxicity in psychiatric patients. However, the mechanisms underlying the cardiovascular side effects of amitriptyline remain largely undefined. Ai...
Objectives: Thyroid hormones regulate all metabolic activities; therefore, it is not amazing that hepatic; renal dysfunctions and lipid alterations are commonly detected in patients with thyroid disorders. This study estimated some biochemical changes in post pubertal hyperthyroi...
Open access
Research Article10.9734/arrb/2019/v31i530063
Amis: Alzheimer’s disease (AD) is one of the most rapidly growing diseases in recent times. Despite extensive research to find an appropriate medicine, there has been no effective drug until now. Study Design: The present study was designated to investigate the therapeutic impact...
Open access
Research Article10.9734/ajbgmb/2023/v13i1283
Aims: Copper oxide nanoparticles (CuO NPs), which have potential hazards for organisms and the environment in a number of applications, have emerged as a prominent class of nanomaterials. Study Design: This study aimed to investigate the effect of copper oxide nanoparticles in ra...
Open access
Research Article10.9734/ajbgmb/2022/v12i4280
Background and Objective: Cancer can develop in any organ at any time; it is a cellular malignancy that causes a breakdown in normal cell-cycle regulation, leading to unchecked proliferation and a lack of differentiation. It is the main factor in human mortality. The therapeutic...
Aim: Silver nanoparticles (Ag NPs) have been utilized in a wide assortment of uses as antimicrobial specialists and have been fused into a few items as mechanical and food items not withstanding natural and clinical applications. Inordinate utilization of nanoparticles might be d...
Background and Objective: Ehrlich ascites carcinoma (EAC) is primarily derived from a murine mammary adenocarcinoma. It is a common tumor an undifferentiated carcinoma with high transplantable capability, no regression, rapid proliferation, shorter life span, 100% malignancy and...
Background: Vepesid (Etoposide) is a chemotherapeutic agent used in many types of tumors, but use it in the treatment is limited because of its toxicity in normal organ tissues. However, rosemary (Rosmarinus officinalis) aqueous extract has shown a protective effect against cance...
Aims: Etoposide (Vepesid) is chemotherapeutic drugs that inhibit topoisomerase II activity and long been used for treatment of human malignancies, where it is a semi-synthetic compound derived from the plant Podophyllum peltatum. The current study was designed to investigate the...
Open access
Research Article10.9734/ajrimps/2019/v7i430126
Objectives: Glivec (Imatinib mesylate) an antineoplastic chemotherapeutic agent used in the treatment of many types of cancer. The current study examines the hepatoprotective potential of grape seed proanthocyandins extract (GSPE) against Glivec induced oxidative stress and toxic...
Open access
Research Article10.9734/ARRB/2017/37766
Objectives: Equigan is an anabolic androgenic steroid that developed for veterinary use to improve the food producing animal growth rate through promoting protein synthesis and muscle growth. The current study aimed to investigate the possible prophylactic effect of star anise ex...
Open access
Research Article10.9734/ARRB/2017/34318
Aims: Silver nanoparticles (Ag NPs) are an important class of nanomaterials used as antimicrobial agents for a wide range of medical and industrial applications.Current study was performed to study the therapeutic effects of chitosan nanoparticles extract towards the treatments w...
Open access
Research Article10.9734/ajrb/2021/v9i330200
Background and Objective: Chitosan, the deacetylated derivative of chitin, is a natural D-glucosamine polymer that can be extracted from the shells of seafood such as lobsters and prawns crabs which have obtained a great interest in cancer therapy. This study aimed to investigate...
Aims: Lead is well known environmental pollutant, which can cause toxic effects in multiple organ systems. Lead originates from various industrial and/or household sources, and enters the body through food and fluid intakes, as well as by inhalation. No sufficient information pre...
Open access
Research Article10.9734/ajrb/2020/v7i230137
Aims: Apoptosis, a type of host-cell death, frequently causes tissue damage in the deaths caused by parasite infections. Current study aimed to study the histopathological and Immunohistochemical changes in rats skeletal muscles after experimental trichinellosis infection. Method...
Background and Objective: Cisplatin (CP), a potent antineoplastic drug and its anti-cytotoxic activity is used to treat many cancer types. The present study aimed to examine the possible modifying effects of ginseng extract against spleen oxidative stress and injury induced by Ci...
Aims: Ehrlich ascites carcinoma (EAC) is a transplantable neoplasia from a malign epithelium; it is a form of ascites when inoculated into the intraperitoneal cavity. This study aimed to investigate the effects of EAC and human hepatocellular carcinoma (HCC) on the liver in mice...