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Deepak Kumar Jha

0000-0002-1979-7940

Publications (11)

Zinc Deficiency and Cancer Progression: Molecular Mechanisms and the Role of Molecular Docking for Zinc-dependent Targets

B D Varshini & Deepak Kumar Jha · Current Journal of Applied Science and Technology · 2026

Zinc is an essential trace element whose influence on human physiology extends from the structural scaffolding of proteins to the catalytic chemistry of enzymes that govern DNA replication and repair, transcriptional regulation, antioxidant defence, and immune signalling. A growi...

Open access Research Article 10.9734/cjast/2026/v45i74720

Neurodegeneration in Alzheimer’s Disease: Integrating Mechanism with Translational Therapeutic Strategies

Ejaz Samiul Hoque, Deepak Kumar Jha & Jaya Saha · Current Journal of Applied Science and Technology · 2026

Alzheimer disease (AD) is a progressive neurodegenerative disease and the most common cause of dementia in the world, which has a gradual deterioration of memory, thinking and autonomy. The AD pathogenesis is a multifaceted and intricate interaction between molecular/cellular pro...

Open access Research Article 10.9734/cjast/2026/v45i54693

Regenerative and Cellular Therapies in Arthritis: Mechanisms, Clinical Evidence and Translational Challenges

Sehba S. Ahmed, Deepak Kumar Jha & Soham Bhattacharjee · Current Journal of Applied Science and Technology · 2026

Background: Arthritis, and especially osteoarthritis and rheumatoid arthritis, contribute to chronic pain and disability and diminished quality of life on a global scale. Treatment approaches that are used currently seem to be based mainly on treating the symptoms without repairi...

Open access Research Article 10.9734/cjast/2026/v45i44681

An Integrated Review of Parkinson’s Disease: Etiology, Differential Diagnosis, Biomarkers, Emerging Therapeutic Approaches, and Translational Models

Mary Brenda Ogwang & Deepak Kumar Jha · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Aims and Objectives: This review aims to provide a comprehensive overview of risk factors, biomarkers, pathophysiology, and synthesis of experimental models of Parkinson’s Disease (PD), with an emphasis on their mechanisms and translational models. Materials and Methods: A narrat...

Open access Research Article 10.9734/jamps/2025/v27i8806

Global Trends and Burden of Diabetes: A Comprehensive Review of Global Insights and Emerging Challenges

Anushree VB, Deepak Kumar Jha & Soham Bhattacharjee · Current Journal of Applied Science and Technology · 2025

Background: Diabetes mellitus is a growing global health challenge, with its prevalence rising rapidly. The increase in diabetes population has been notably higher in lower and middle-income nations with resulting in inequalities in the global disease burden. Aim: This review is...

Open access Research Article 10.9734/cjast/2025/v44i74580

Overview of T-Cell Therapy: An Enormous Breakthrough in the Fight against Cancer

Saroj Kumar Sah & Deepak Kumar Jha · Current Journal of Applied Science and Technology · 2024

Background: Cancer cells are cells which have relinquished their capacity to adhere to typical regulatory controls. As cancer progresses, it can spread to adjacent tissues, posing   significant risk to one's survival. Current approach towards cancer management involves; Surgery,...

Open access Research Article 10.9734/cjast/2024/v43i74402

Overview of Cellular Therapy: Reshaping the Wound in Diabetic Foot Ulcer

Mehdi Fathima & Deepak Kumar Jha · Current Journal of Applied Science and Technology · 2024

Background: Diabetic Foot Ulcer (DFU) occurs due to a number of factors that compromises the peripheral neuropathy, mechanical changes in conformation of the bony architecture of the foot. Different types of cellular therapy and particularly Stem cells have been used by various m...

Open access Research Article 10.9734/cjast/2024/v43i74403

Pharmacological Evaluation of Moringa oleifera on Collagen- Induced Arthritis in Rats

C. V. Mohan, Sandipan Chatterjee & Deepak Kumar Jha · Journal of Pharmaceutical Research International · 2022

Background and Objective: Arthritis associated with oxidative stress and chronic inflammation has been a major health problem among the people worldwide. The present study was aimed to investigate the potential anti-arthritis activity of the methanolic extract of leaves of Moring...

Open access Research Article 10.9734/jpri/2022/v34i54B7240

Evaluation of In-vivo Anticancer Activity Choerospondias axillaris in Swiss Albino Mice Models

Zohreh Elyasi, U. Rajashekhar, Deepak Kumar Jha & Jeevan Khadka · Journal of Pharmaceutical Research International · 2022

Background and Objective: The fruits of the plant, Choerospondias axillaris are one of the richest sources of flavonoids phenol and vitamin C that have been shown to possess a variety of biological activities. The present study was aimed to study the potential anti-cancer activit...

Open access Research Article 10.9734/jpri/2022/v34i54A7237

An Investigation of Insulinotropic Potential of Herbal Plants for Management of Diabetes

Yousef Ahmed Saleh Haimed, Pankaj Kumar Sharma, Deepak Kumar Jha & Jaya Sharma · Journal of Pharmaceutical Research International · 2022

The Insulinotropic hormone glucagon-like peptide-1, which has been proposed as a modern treatment for management of diabetes, is metabolized extremely with the aid of dipeptidyl peptidase-IV. Inhibitors on dipeptidyl peptidase-IV enhance the level of glucagon-like peptide-1, as h...

Open access Research Article 10.9734/jpri/2022/v34i44A36329

Anti-Type I Diabetic Activity of the Methanolic Extract of Aegle marmelos on Streptozotocin Induced Rat Model

Yousef Ahmed Saleh Haimed, Pankaj Kumar Sharma & Deepak Kumar Jha · Journal of Pharmaceutical Research International · 2022

Aegle marmelos, generally acknowledged as Bael, is being ancient in Ayurveda for the therapy of a number of disorders. All the components on it tree along with stem, bark, root, leaves, fruit and seeds at all stages of maturity have medicinal virtues and have been recorded in Eth...

Open access Research Article 10.9734/jpri/2022/v34i17B35766