Adrenoleukodystrophy (ALD) is caused by an X-linked inborn error of metabolic disorder due to the mutation of ATP binding cassette subfamily D member 1 (ABDC 1) gene. Three types of ALD cerebral form affect children aged 5-10, while the adrenomyeloneuropathy (AMN) form affects mi...
The gastrointestinal systems (GIT) and endocrine systems are integrated into a well-coordinated complex to meet the metabolic needs of the body. The endocrine functions and possible dysfunctions are less emphasized in the medical curriculum. Hormones are synthesized and released...
Adedeji Okikiade, Aromedonghene Osharode, Olayinka Oloye-Afolayan, Damisola Ogunesan, Oyewole Adijat, K. Ubah Chibuike & Kevin Browne·Advances in Research·2022
The human body is a complex structure with the innate ability to protect, defend, repair, and heal after damage or disease. For decades, medicine has faced problems that need the evolution of standard treatments and finding a way to accelerate the regenerative capabilities of the...
Open access
Research Article10.9734/air/2022/v23i6920
Adedeji Okikiade, Aromedonghene Osharode, Adijat Oyewole, Damisola Ogunesan, Dolapo Oladejo, Ibukunoluwa Oshobu & Kevin Browne·Asian Journal of Medicine and Health·2022
Osteoarthritis (OA) is the most seen form of arthritis, affecting a population of about 3.3 to 3.6% worldwide. In the ranking, it is the 11th most incapacitating disease worldwide, and in about a 43million people, it causes mild to severe disability. Estimated that 80% of the po...
Open access
Research Article10.9734/ajmah/2022/v20i1030506
Kluver Bucy Syndrome (KBS) was initially reported by Sanger Brown and Edward Albert Sharpey-Schafer. In 1939, a bilateral temporal lobectomy was conducted on a Rhesus monkey named Aurora. Three weeks after this procedure, Aurora began to exhibit behavioral changes. These behavior...
Open access
Research Article10.9734/indj/2022/v18i3350
Krabbe disease (or Globoid cell leukodystrophy) is a rare mutation of a gene found on chromosome 14q31 responsible for the production of the enzyme called galactocerebrosidase (G ALC), which breaks down two galactolipids; galactosyl-ceramide and galactosylsphingosine (psychosine)...
Adedeji Okikiade, Edward Taylor, Norhan Abdulrahman, Oyeniyi Imoleayo, Miriam Tikanide, Aromedonghene Osharode & Damisola Ogunesan·International Research Journal of Oncology·2022
Paraneoplastic Neurological Syndromes (PNS) are a rare spectrum of non-metastatic manifestations likely secondary to T-cell or auto-antibodies induced neuronal dysfunction or cell death and are mostly associated with soft tissue cancers. PNS arises from either the cell membrane b...
This is a review article with narratives on a rare discussion of existence of hormonal dysfunctions in variants of renal tubular acidosis (RTA), acquired and congenital renal tubular disorders, with focus on the molecular and physiological defects. The renal tubules primarily fun...