Computational Identification of YQG-Like Small-molecule Inhibitors Targeting TIM-3 for Cancer Immunotherapy
Winner Amaka Egejuru, Abel Ujaigbe Egbemhenghe, Bamidele Samson Omotara, Christiana Oluwaseun Aderemi, Ibidun Blessing Isaac, Emmanuel Parkay Oladokun, Pruthvirajsinh Rajendrasinh Solanki, Ihunanya Meejay Kanu, Christopher Ddamulira, Ibrahim Tope Abdulrasaq, Yemisi Elizabeth Asibor, Onyinyechi Vera Ofoegbu, Sheriff Olabisi Ogunyemi, Cyril Obaro Agadagba, Muhammad Qasim Ali & Olajide Enoch Aderemi · International Journal of Biochemistry Research & Review · 2025
Aims: To identify potential small-molecule inhibitors of T-cell immunoglobulin and mucin domain-3 (TIM-3) through computational approaches and evaluate their interactions, stability, and structural dynamics. Study Design: A computational drug discovery study utilizing virtual scr...