Chimaobi O. Ugorji

Antimicrobial and Antioxidant Studies of the Leaf Extract and Fractions of Sabicea brevipes Wernham (Rubiaceae)

Chimaobi O. Ugorji, Janefrances N. Ihedioha, Matthias O. Agbo, Nwachukwu R. Ekere, Felix I. Nwafor & Emmanuel I. Odoemelam · International Journal of Biochemistry Research & Review · 2019

Phytochemical analysis, antimicrobial and antioxidant properties of the leaf extract and fractions of Sabicea brevipes were studied. The leaves were defatted and the marc extracted with methanol. The extract was further purified by solvent-solvent partitioning using n-hexane, eth...

Open access Research Article 10.9734/ijbcrr/2019/v27i230119

Synergistic Effects of Polyphenol-Terpenoid Combinations on NLRP3 Inflammasome-Mediated Neuroinflammation: A Mini Review

Paul Chinwuba, Chimaobi O. Ugorji, Daniel L. Ajaghaku, Winifred O. Amattah, Amara A. Ajaghaku, Onyesife C. Obiageli, Zogini U. Confidence, Victor T. Ezeifeh & Okoro O. Kingsley · Journal of Pharmaceutical Research International · 2025

Neuroinflammation driven by the NLRP3 inflammasome is a key mechanism in many neurological disorders. While plant-derived polyphenols and terpenoids individually show anti-inflammatory potential, their synergistic effects remain underexplored. This review highlights the enhanced...

Open access Research Article 10.9734/jpri/2025/v37i117762