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Charles Fokunang

Publications (10)

Toxicological Investigations of Ethanolic Leaves Extract of Dissothis thollonii (Melastomataceae)

Donald Sédric Tala, Siméon Pierre Chegaing Fodouop, David Ngoudjou Tsafack, Norbert Kodjio, Charles Fokunang & Donatien Gatsing · Journal of Pharmaceutical Research International · 2018

Dissotis thollonii is widely used in Cameroon for the treatment of typhoid fever, gastrointestinal disorders, inflammation, kidney diseases, pregnancy control and sinusitis. However there is lack of experimental data on its possible toxicity. The aim was to investigate acute and...

Open access Research Article 10.9734/JPRI/2018/39412

Assessing the Impact of Antiretroviral Therapy on CD4, Hemoglobin Level and Weight in HIV Infected Children (0-15 Years) Residing in Nkambe, North West Region, Cameroon

Lem Edith Abongwa, Ntonifor Helen Ngum, Nantia Akono Edouard, Nfor Germaine & Charles Fokunang · Microbiology Research Journal International · 2016

Background: Antiretroviral therapy (ART) has greatly decreased the mortality and morbidity of children living with HIV by reducing the viral load, increase CD4 count thus improving the health of HIV clients. This study seeks to assess the impact of ART on CD4+ Cell Count, weight...

Open access Research Article 10.9734/BMRJ/2016/26088

Cost-Effectiveness of Routine Outpatient Follow-Up Intervals in Adults with Sickle Cell Anemia: A Pilot Study from Cameroon

Ngoe Samuel Bakia, Chetcha Bernard Chenmagni, Eustace Bonghan Berinyuy, Estella Achick Tembe-Fokunang, Mbappe Herguel Epoh & Charles Fokunang · Journal of Pharmaceutical Research International · 2026

Background: Sickle cell disease (SCD) requires lifelong management and monitoring, yet in Cameroon, many adults seek care only during crisis, driving hospitalizations and healthcare costs. This study examined whether adults with sickle cell anemia (SCA) attending ≥3 routine follo...

Open access Research Article 10.9734/jpri/2026/v38i37824

Substandard and Falsified Medicines in West and Central Africa: A Systematic Review of Prevalence, Detection Methods, and Regulatory Gaps

Samuel Ngum, Gerald Ngo Teke, Signang Alberic Ndonku, Mary Bi Suh Atanga, Estella Achick Tembe-Fokunang & Charles Fokunang · Journal of Advances in Medicine and Medical Research · 2025

Introduction: Substandard, falsified, unlicensed, and unregistered medicines pose a significant threat to public health, particularly in West and Central Africa, where weak regulatory frameworks and informal pharmaceutical markets facilitate their widespread distribution. This sy...

Open access Research Article 10.9734/jammr/2025/v37i65859

Phytochemical Screening and Evaluation of the Anti Ulcer Activity of Dacryodes edulis (Burseraceae) Leaf Extracts in Wistar Rats

Nomo Honore, Tembe Estella Fokunang, Bayaga Herve, Njinkio Nono Borgia, Mbacham Wilfred & Charles Fokunang · International Research Journal of Gastroenterology and Hepatology · 2023

Peptic ulcer disease is a chronic condition of the gastrointestinal tract that results from an imbalance between protective and aggressive factors of the gastric mucosa. Many synthetic drugs are used for the treatment of this disease, but they are costly and exhibit limited effic...

Open access Research Article

Phytochemical Characterization and Acute Toxicity Investigation of the Hydroethanolic Leaf Extract of Dacryodes edulis (G. Don) H.J. Lam on Wistar Rat Models

Nomo Honore, Tembe Estella Fokunang, Bayaga Herve, Njinkio Nono Borgia, Mbacham Wifred & Charles Fokunang · South Asian Research Journal of Natural Products · 2023

Medicinal plants play an important role in the management of several diseases and have become widespread. However, people use plant species without considering the toxicity they may present. In a previous study, the hydroethanolic leaf extract of D edulis showed a very good anti-...

Open access Research Article

Clinical Clusters of Sickle Cell Anemia: Exploring the Impact of Lifestyle, Environmental, and Socioeconomic Influences in Cameroon

Ngoe Samuel Bakia, Mbappe Herguel Epoh, Grâce Bissohong, Pouth Guy Hott, Eustace Bongang Berinyuy, Chetcha Bernard Chenmagni & Charles Fokunang · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: Despite growing evidence that exogenous factors such as environmental conditions, influence the clinical severity of sickle cell anemia, their impact remain poorly understood in Cameroon. This study explores clinical clusters of sickle cell anemia and their associatio...

Open access Research Article 10.9734/jamps/2025/v27i7805

Evaluation of Anti-Salmonella Activity and Acute Toxicity of Azadirachta indica (A. Juss) Seed Oil

Yede Marie Paule, Estella Achick Tembe, Mbong Grace Anih, Bayaga Herve, Njinkio Nono Borgia, Gonsu Kamga Hortense & Charles Fokunang · South Asian Research Journal of Natural Products · 2023

Bacterial infections by Salmonella remain a real public health threat causing each year, more than 1.2 million deaths worldwide. The treatment by antibiotics is usually compromised due to the emergence of multi-resistant strains, supply chain problems and the high cost of medicin...

Open access Research Article

Ethopharmacological Approach, in vivo Antidiarrhoeic Properties of Aqueous Leaf Extract of Mallotus oppositifolium (Euphorbiaceae) and Isolation of Antidiarrheal Compound

Roger Zintchem, Gaëtan Olivier Fankem, Joseph Ngakou Mukam, Antoine Kada Sanda, Estella Tembe Fokunang, Borgia Njinkio, Paul Aimé Noubissi, Pascal Sonna, Charles Fokunang & René Kamgang · European Journal of Medicinal Plants · 2023

Mallotus oppositifolium. Müll. Arg (Euphorbiaceae) is commonly used in the Center Region of Cameroon against diarrheal syndromes and joint pains. In order to provide a scientific basis for its use in the traditional treatment of diarrhea, we proposed to evaluate the effects of aq...

Open access Research Article 10.9734/ejmp/2023/v34i71145

Phytochemical Screening, Evaluation of Anti-Peptic Ulcer Activities of Aqueous Leaf Extract of Neem Azadirachta indica A. Juss (Meliaceae) in Wistar Rats

Tembe Fokunang Estella, Ndi Sirri Akwen, Mbong Grace Annih, Ashu Michael Agbor, Dobgima John Fomnboh, Tchadji Mayoudom Vanessa Edwige, Bayaga Herve, Njinkio Borgia Nono, Roger Zintchem, Yolande Gnagne Koffi & Charles Fokunang · International Research Journal of Gastroenterology and Hepatology · 2022

Introduction: Peptic ulcer disease (PUD) is a major public health concern, affecting up to 10% of the world’s population. This disease results from an imbalance between the gastro protective and aggressive factors of the gastric mucosa. Prevalence of PUD is about 10% in Cameroon...

Open access Research Article