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C. D. Luka

Publications (11)

Effect of Processing Unripe Plantain (Musa paradisiaca) Extracts on Some Biochemical Parameters in Alloxan-Induced Wistar Rats

C. D. Luka, J. C. Oyeocha, M. K. Kwarpo & G. Istifanus · South Asian Research Journal of Natural Products · 2018

Unripe plantain is used for management of diabetes mellitus in Nigeria, the possible effect of its methods of processing on some biochemical parameters has not been investigated. The objective of this study is to determine the effect of methods of processing unripe plantain on bl...

Open access Research Article

Effect of Aqueous Extract of Dodonaea viscosa Linn on Some Biochemical Parameters in Alloxan-induced Diabetic Rats

C. D. Luka, G. Istifanus, M. George & N. S. Jesse · Current Journal of Applied Science and Technology · 2018

This study evaluates the effect aqueous leaf extracts Dodonaea viscosa Linn on alloxan-induced diabetic rats. Sixty grams of Dodonaea viscosa Linn leaf that has initially been pulverized was used to produce the aqueous extract. Sixteen male albino rats were randomly divided into...

Open access Research Article 10.9734/CJAST/2018/36991

Effect of Aqueous Seed Extract of Terminalia catappa Linn on Some Biochemical Parameters in Alloxan-induced Diabetic Rats

C. D. Luka, G. Istifanus, A. Olatunde & Z. Eli · Journal of Applied Life Sciences International · 2017

This study is aimed at determining the anti-diabetic activity of aqueous seed extract of Terminalia catappa Linn on some biochemical parameters in alloxan-induced diabetic rats. Alloxan-induced diabetic rats were administered orally with aqueous extract of Terminalia catappa Linn...

Open access Research Article 10.9734/JALSI/2017/34296

Phytochemical Studies of Different Fractions of Galega officinalis Extract and Their Effects on Some Biochemical Parameters in Alloxan-Induced Diabetic Rats

C. D. Luka, G. I. Adoga & G. Istifanus · European Journal of Medicinal Plants · 2017

Galega officinalis Linn (Goat’s rue) is popularly called sakpani in Hausa speaking part of Nigeria. The Plant belongs to the family Leguminoseae. G. officinalis is chiefly used as an antidiabetic plant because of its ability to reduce blood sugar levels. The plant has positive ef...

Open access Research Article 10.9734/EJMP/2017/32145

Effect of Aqueous Extracts of Flower, Leaf, Stem and Root of Ageratum conyzoides L on Glucose, Lipid Profile and Liver Markers on Streptozocin Induced Diabetic Rats

G. Istifanus, C. D. Luka & T. O. Johnson · South Asian Research Journal of Natural Products · 2022

Type 2 diabetes is the most recorded form of diabetes. It accounts for about 80% to 90% of all recorded cases of diabetes mellitus. The use of plant medicine is a very common practice from ancient time and it is considered the safer and less expensive therapeutic strategy for man...

Open access Research Article

Lethal dose Examination and Effect of Different Part Extracts of Ageratum conyzoides L on Hematology and Serum Electrolytes of Streptozotocin Induce Diabetic Rats

G. Istifanus, C. D. Luka & T. O. Johnson · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2022

Diabetes mellitus (DM) is a disease condition caused by decreased insulin production in the pancreas or as a result of the inability of insulin to act on target tissues that activate the absorption of blood glucose. This subsequently leads to an increased concentration of glucose...

Open access Research Article 10.9734/ajbgmb/2022/v11i330270

Antidiabetic Activity of Physalis angulata in Streptozotocin Induced Diabetic Wistar Albino Rats

C. E. Mafuyai, C. D. Luka, M. K. Jiyil & . Okon · Journal of Advances in Biology & Biotechnology · 2020

Background: Physalis angulata have been extensively used for the management of diabetes in folklore medicine, in Nigeria. Aim: The present study aimed to investigate the antidiabetic effect of aqueous extract of Physalis angulata and its potential mechanisms in streptozotocin-ind...

Open access Research Article 10.9734/jabb/2020/v23i1130190

Effect of Aqueous Extract of Zingiber officinale (Ginger) on Some Biochemical Parameters in Streptozotocin-induced Diabetes Rats

M. K. Jiyil, C. D. Luka, C. E. Mafuyai & N. Pamela · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2019

Background: Appreciable number of medicinal plants are used for the treatment of diabetes in Nigeria. Aim of the Study: The present study aimed to investigate the antidiabetic activity of Zingiber officinale extracts and its potential mechanisms in streptozotocin-induced diabetic...

Open access Research Article 10.9734/ajrimps/2019/v8i1-230131

Physicochemical, Nutritional and Antioxidant Properties of Syzygium malaccense Extracted with Different Solvents

M. Omojufehinsi, I. Y. Longdet & C. D. Luka · Asian Journal of Food Research and Nutrition · 2023

Background: Underutilized plants are nutritionally rich and contain variety of phytochemicals which need to be explored for their contribution to the improvement of human health and economic value. Aim: To evaluate the physicochemical characteristics, nutrient, phytochemicals and...

Open access Research Article

Effect of Ethanolic Leaf Extract of Sarcocephalus latifolius on Some Biochemical Parameters in Alloxan Induced Diabetic Rats

M. N. Ndukwe, G. I. Adoga & C. D. Luka · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

This research project was carried out to investigate the biochemical effect of Sarcocephalus latifolius leaf extract in alloxan induced diabetic rats. The study was carried out for about 12 months in the department of Biochemistry University of Jos, Jos, Nigeria and Prestige medi...

Open access Research Article 10.9734/JAMPS/2017/34311

Evaluation of the Antidiabetic Effects of Cashew Plant (Anacardium occidentale) on Alloxan-Induced Wistar Albino Diabetic Rats

M. K. Jiyil, K.G Wilson, C. E. Mafuyai, C.P Japhet, M.I. Shago & C. D. Luka · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

According to the World Health Organisation, over 537 million adults currently live with diabetes. Despite the availability of pharmacological treatments such as insulin and oral hypoglycemic agents, these options often come with significant drawbacks. As a result, there is increa...

Open access Research Article 10.9734/ajbgmb/2025/v17i10496