Boubacar Mahamadou

Polymorphism of pfk13-propeller in Niger: Detection of Novel Mutations

Ibrahim Maman Laminou, Mahaman Moustapha Lamine, Boubacar Mahamadou, Oumou Maïga Ascofaré & Alioune Dièye · Journal of Advances in Medicine and Medical Research · 2017

Aim: Artemisinin resistance was confirmed in Southeast Asia in 2009, and a molecular marker of resistance to artemisinin as point mutations in the region of the kelch13 gene (k13) coding for the C-terminal propeller domain of Kelch13 (K13-propeller) gene, was discovered in Cambod...

Open access Research Article 10.9734/JAMMR/2017/34192

Detection of Plasmodium falciparum K13 Propeller A569G Mutation after Artesunate-amodiaquine Treatment Failure in Niger

Ibrahim Maman Laminou, Moustapha Mahamane Lamine, Ibrahim Arzika, Boubacar Mahamadou, D. Gora & A. Dieye · Journal of Advances in Biology & Biotechnology · 2018

Background: Artemisinin (ART) resistance is a problem that may compromise the elimination of malaria. It is associated with point mutations in the kelch gene PF3D7_1343700 or K13 propeller (pfk13). A recent worldwide map of pfk13 polymorphisms revealed more than 100 non-synonymou...

Open access Research Article 10.9734/JABB/2018/42872