Beyond Linear Trend Estimation: Uncertainty-weighted Generalised Additive Mixed Modelling of Global Liver Disease Burden
Francis Ayiah-Mensah, Bamidele Mustapha Oseni, Senyefia Bosson-Amedenu, Luyton Asare & Emmanuel Ayitey · International Research Journal of Gastroenterology and Hepatology · 2026
Background: Non-linear models, unequal (random) estimation uncertainty, repeated observations, and temporal autocorrelation are not adequately addressed in conventional liver-burden studies, which typically use percentage changes or linear annual trends. The purpose of this study...
Open access
Research Article
10.9734/irjgh/2026/v9i1161