B. R. Challa

In vitro- In vivo Correlation Studies of Modified Release Tolterodine Tablet Dosage form in Rabbits

P. Srinivasa Babu, S. K. Rihana Parveen, K. B. Chandrasekar & B. R. Challa · Journal of Pharmaceutical Research International · 2014

Tolterodine is an antimuscarnic drug that is used for sympathetic treatment of urinary incontinence. Tolterodine modified release tablet, was investigated in rabbit for pharmacokinetic and in vitro–in vivocorrelation studies. Tablets were prepared and in vitro release was studied...

Open access Research Article 10.9734/BJPR/2014/9950

In vitro–In vivo Correlation Studies of Modified Release Solifenacin Tablet Dosage Form

P. Srinivasa Babu, SK. Rihana Parveen, K. B. Chandrasekar, B. R. Challa & Bahlul Zayed Sh. Awen · Journal of Scientific Research and Reports · 2014

A modified release formulation of Solifenacin tablet, was investigated in rabbit for pharmacokinetic and in vitro–in vivo correlation studies. In vivo study was conducted in New Zealand albino male rabbit plasma and In vitro release studies were conducted in simulated gastric flu...

Open access Research Article 10.9734/JSRR/2014/9951

Quantification of Etravirine in Rat Plasma by LC-MS/MS and Application to a Pharmacokinetic Study

Khagga Bhavyasri, V. Murali Balaram, R. Nageswarao, D. Rambabu, M. Ajitha & B. R. Challa · Journal of Scientific Research and Reports · 2015

A rapid, rugged and reproducible, higher in sensitivity bio-analytical method was developed for quantification of Etravirine (EV) in rat plasma by LC-MS/MS. Etravirine15N2, 13C1 (EVIS) used as an internal standard (IS). Chromatography was performed with ZORBAX Eclipse Plus Phenyl...

Open access Research Article 10.9734/JSRR/2015/12219