The JAK2 V617F Mutation in Chronic Myeloid Leukaemia within a BCR-ABL Positive Cohort of Beninese Patients
S. Azonbakin, B. Houssou, I. Azannai, B. Awede, R. MassI, M. Adjagba, A. Agbalinsou, L. Anani, R. Darboux, F. Gangbo & A. Laleye · International Blood Research & Reviews · 2018
Chronic myelogenous leukaemia (CML) is an acquired myeloproliferative disorder (MPD) characterized by a chromosomal abnormality (the Philadelphia chromosome) that causes the chimeric BCR-ABL oncogene. An acquired genetic mutation in exon 12 of the JAK2 tyrosine kinase gene leadin...