Aims and Study Design: Epidermal growth factor receptor (EGFR) regulates a number of cellular processes, including cell motility, proliferation, differentiation and survival. EGFR mediated signal transduction via mitogen activated protein kinase (MAPK) modulates expression and ac...
Open access
Research Article10.9734/ARRB/2016/27388
Aims: Breast cancer is the most prevalent cancer affecting women worldwide. Aberrant signalling through the phosphatidylinositol 3’ kinase (PI3K) and extracellular signal regulated kinase (ERK) pathways promotes metastatic spread of breast carcinomas. As prevalent chemotherapeuti...
Open access
Research Article10.9734/arrb/2025/v40i42230
Aims and Study Design: Overexpression of epidermal growth factor receptor (EGFR) and its phosphorylated form (p-EGFR) in breast carcinomas has been associated with an increase in invasive potential and decreased survival. EGFR mediated signal transduction has been reported to be...
Open access
Research Article10.9734/BBJ/2016/28977