Objectives: To investigate the effect of paricalcitrol as a vitamin D analogue on erectile dysfunction and on the penile expression of superoxide anion generationand nitric oxide synthase (NOS) isoforms instreptozotocin-induced diabetic rats models. Methods: Male Sprague-Dawley r...
Open access
Research Article10.9734/JAMMR/2018/41829
Background: This study investigated the potential therapeutic effect of simvastatin and vildagliptin and their combination on angiogenesis in diabetic hind-limb ischemia. Methods: 60 Sprague-dawely rats were divided into 5 groups, group A (normal control), group B (diabetic ische...
Open access
Research Article10.9734/BJMMR/2014/10804
Back Ground and Objectives: Despite the therapeutic benefits of cisplatin (CDDP), its use clinically is often limited due to dose-related nephrotoxicity. On the meanwhile, DPP 4 inhibitors could attenuate kidney injury, so in the present work, it was aimed to investigate the effe...
Open access
Research Article10.9734/BJPR/2014/9297
Doxorubicin (DOX) has been used in variety of human malignancies for decades. Despite its efficacy in cancer, clinical usage is limited because of its cardiotoxicity, which has been associated with oxidative stress. The possible protective mechanisms of ivabradine, a selective in...
Open access
Research Article10.9734/BJMMR/2015/10764