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Alphonsus D’souza

Publications (3)

A Review Article on Triazoles and its Pharmacological Activities

Alphonsus D’souza, K. D. Venuprasad, Prashant Nayak & Lisha K. Poonacha · Journal of Pharmaceutical Research International · 2021

Despite the fact that triazole was first synthesised over a century ago, it continues to unique the interest of chemists, biologists, technologists, and other experts.  Triazoles  have been shown to have antiviral, anti-inflammatory, anti-fertility, anti-tubercular, antimicrobial...

Open access Research Article 10.9734/jpri/2021/v33i43A32491

A Synthesis of Substituted 1,3,4-Oxadiazole, Pyrazole Deravatives and It’s Biological Activities

Alphonsus D’souza, Prashant Nayak, Prasanna Shama Khandige & Pankaj Kumar · Journal of Pharmaceutical Research International · 2021

Aim: Nicotine Substituted  1,3,4 Oxadiazole and pyrazole moieties were integrated by utilizing hydrazide as halfway .Oxadiazole were acquired by two techniques one is by utilizing PoCl3 within the sight of fragrant corrosive ,other is by utilizing carbon disulphide in the presenc...

Open access Research Article 10.9734/jpri/2021/v33i37B32048

Synthesis, Insilico and Antibacterial Activity Studies of Substituted Dihydro-1, 2-Oxazole Benzopyran-2-One Hybrids

Alphonsus D’souza, Pankaj Kumar, Abhishek Kumar, Soundarya M. Rai & Prashant Nayak · Journal of Pharmaceutical Research International · 2021

A series of substituted dihydro-1, 2-oxazole benzopyran-2-one (SR1-SR6) were synthesized through the intermediate substituted benzopyran-2-one chalcones and were characterized using spectral analysis.   Compounds were docked with receptor DNA Gyrase B (PDB code: 5L3J) to know its...

Open access Research Article 10.9734/jpri/2021/v33i35A31882