Ahmet Kucuk, Erkan Topkan, Esma Didem Ikiz, Nulifer Kılıc Durankus, Sukran Senyurek, Eyub Yasar Akdemir, Duygu Sezen, Yasemin Bolukbasi, Ugur Selek & Berrin Pehlivan·International Research Journal of Oncology·2020
Brain metastases (BMs) represent the commonest intracranial tumours which occur approximately 30% of all adult patients presenting with solid cancers. The BMs do not only reduce the survival expectations but negatively alter the quality of life measures as well. For decades, surg...
Erkan Topkan, Ahmet Kucuk, Sukran Senyurek, Duygu Sezen, Nulifer Kılıc Durankus, Eyub Yasar Akdemir, Yucel Saglam, Yasemin Bolukbasi, Berrin Pehlivan & Ugur Selek·Journal of Cancer and Tumor International·2020
As a notable cause of cancer-related morbidity and mortality, brain metastases (BMs) represent the most prevalent intracranial tumors arising in up to 40% of all adult solid tumors during the course of treatment. Intracranial stereotactic radiosurgery (SRS) or fractionated stereo...
Open access
Research Article10.9734/jcti/2020/v10i230122
Erkan Topkan, Ahmet Kucuk, Nulifer Kilic Durankus, Sukran Senyurek, Eyub Yasar Akdemir, Duygu Sezen, Esma Didem Ikiz, Yasemin Bolukbasi, Berrin Pehlivan & Ugur Selek·International Research Journal of Oncology·2020
Brainstem metastases account only for 3% to 5% of all intracranial metastasis. However, brainstem metastases undoubtedly represent a significant source of severe morbidity and mortality in affected patients with estimated average survival duration of only less than 6 months. Surg...
Erkan Topkan, Ahmet Kucuk, Sukran Senyurek, Duygu Sezen, Nulifer Kilic Durankus, Eyub Yasar Akdemir, Esma Didem Ikiz, Yasemin Bolukbasi, Berrin Pehlivan & Ugur Selek·Journal of Cancer and Tumor International·2020
Brain metastases (BMs), the most frequent intracranial tumors, are diagnosed in approximately 30% of all adult patients over the span of planned treatment against a broad spectrum of solid cancers. The prognosis of patients presenting with BM is bleak with an expected median OS o...
Open access
Research Article10.9734/jcti/2020/v10i130117
A significant contributor to cancer-related morbidity and mortality worldwide is head and neck cancer (HNC). Depending on the affected site, its etiology may include risk factors like geographic differences, genetic predisposition, gender, age, type of diet, smoking and/or alcoho...
Open access
Research Article10.9734/jammr/2022/v34i234872
Radiation therapy is the most common cause of cancer-related trismus. Radiation therapy can lead to fibrosis and hypoxia in the temporomandibular joint ligaments, synovial fluid, and masticatory muscles. This makes it difficult for patients to move their jaws and eventually leads...
Open access
Research Article10.9734/jammr/2022/v34i2231599
Osteoradionecrosis of the jaws (ORNJ) is a severe radiotherapy (RT) complication that occurs in 2% to 22% of individuals with head and neck cancers (HNC) who are treated with RT or concurrent chemo-RT. The accurate diagnosis of ORNJ is crucial for appropriate and prompt managemen...
Open access
Research Article10.9734/jcti/2022/v12i430187
One of the most serious and debilitating complications of radiation therapy (RT) for patients with head and neck cancer (HNC) is osteoradionecrosis of the jaws (ORNJ). ORNJ is defined as radiation-induced ischemic bone necrosis with soft tissue necrosis in the absence of primary...
Open access
Research Article10.9734/jammr/2022/v34i2131522
Head and neck cancers (HNC) account for 10–15% of all cancers globally. Curative radiation therapy (RT) and concurrent chemoradiotherapy (CCRT) with or without surgery are widely accepted standard treatment modalities for these patients. Radiation-induced fibrosis is one of the s...
Open access
Research Article10.9734/acri/2022/v22i530288
Perpetual advances in the diagnostic tools, local plus systemic cancer treatments, and ensued lengthened survival times led to striking increments in the incidence rates of brain metastases (BMs), with a collective incidence range of 20-40% for all solid cancers. Stereotactic rad...
Open access
Research Article10.9734/jammr/2021/v33i230807
Yucel Saglam, Yasemin Bolukbasi, Ali Ihsan Atasoy, Fatih Karakose, Vildan Alpan, Ugur Selek, Ahmet Kucuk, Berrin Pehlivan & Erkan Topkan·Advances in Research·2020
Stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT) have settled down in the center of modern palliative and recently curative intent treatments in the last two decades. Being special, technology-driven, direct knowledge and experience based clinical procedu...
Open access
Research Article10.9734/air/2020/v21i730216
Yasemin Bolukbasi, Ugur Selek, Duygu Sezen, Nulifer Kilic Durankus, Eyub Yasar Akdemir, Sukran Senyurek, Ahmet Kucuk, Berrin Pehlivan & Erkan Topkan·Journal of Cancer and Tumor International·2020
Stereotactic radiosurgery (SRS) has been utilized broadly for brain metastases not only for intact ones but as well as of late for the postoperative cavity of metastases after surgery, due to the advantages of SRS to preserve neurocognitive functions, maintain local control and p...
Open access
Research Article10.9734/jcti/2020/v10i230123