Computational Evaluation of Some Schiff-Bases of Phenylisocytosine as Potent Inhibitors of Plasmodium falciparum Transketolase in Anti-Malarial Drug Discovery
Opeyemi Emmanuel Atanda, Adeola Folasade Ehigie, Tawakalit Abimbola Adisa, Lamidi Waheed Babatunde Olaniyan, Temitope Tunji Odunitan, Olatomide Ayodeji Fadare, Mary Oyindamola Jesulade, Adedamola Onikepo Adesina & Leonard Ona Ehigie · International Journal of Biochemistry Research & Review · 2025
Background: The increasing prevalence of drug-resistant Plasmodium falciparum strains, particularly resistance to frontline therapies such as artemisinin and its derivatives, poses a significant challenge to malaria control and eradication efforts. This necessitates the developme...
Open access
Research Article
10.9734/ijbcrr/2025/v34i41021