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A. A. Chernonosov

Publications (3)

Extraction Procedure Optimization of Atenolol from Dried Plasma Spots

A. A. Chernonosov & V. V. Koval · Journal of Pharmaceutical Research International · 2019

Aims: Atenolol is one of the β-blockers widely used for the treatment of hypertension and other cardiovascular diseases. To simplify the methods for determining of drugs concentrations in blood and plasma the dried spots assays (dried blood spots or dried plasma spots) could be u...

Open access Research Article 10.9734/jpri/2019/v31i630330

Parameters Optimization of Edoxaban Extraction from Dried Plasma Spots

G. A. Zakabluk, V. V. Koval & A. A. Chernonosov · Journal of Pharmaceutical Research International · 2020

Aims: Edoxaban is a direct-acting oral anticoagulant, being a highly selective, direct and reversible factor Xa inhibitor. Edoxaban is used to treat and prevent blood clots such as deep vein thrombosis and pulmonary embolism. The dried spot technic, including dried blood spots an...

Open access Research Article 10.9734/jpri/2020/v32i3230941

Optimization of the Extraction Procedure of Apixaban from Dried Rat Plasma Spots

L. V. Aksenova, V. V. Koval & A. A. Chernonosov · Journal of Pharmaceutical Research International · 2020

Aims: Apixaban is an anticoagulant used to treat and prevent blood clots, as well as to prevent stroke in people with atrial fibrillation. The dried spot analyses, including dried blood spots and dried plasma spots, are used to simplify techniques for determining drug concentrati...

Open access Research Article 10.9734/jpri/2020/v32i530430