molecular surveillance

Molecular and Genomic Malaria Diagnostics for Elimination and Resistance Surveillance: A Critical Narrative Review of Analytical Performance, Epidemiological Inference and Programmatic Translation

Robinson Ndifrekeabasi Itek & Evelyn Orevaoghene Onosakponome · Microbiology Research Journal International · 2026

Malaria control has become dependent on two technologies whose limitations are now well documented: light microscopy, which cannot reliably detect the low-density infections that sustain transmission, and antigen-detecting rapid diagnostic tests, whose principal target is being d...

Open access Research Article 10.9734/mrji/2026/v36i101789

Sentinel surveillance of the WHO-Validated Pfkelch13 C580Y Artemisinin Resistance Marker in Plasmodium falciparum Isolates from Bangui, Central African Republic

Moynam Ekte Heredeibona, Aroun Abdel Nassir, Bejendo Dan-Houron, Héritier Obed Lango, Christelle Luce Bobossi, Coretha Bokia Baguida, Ernest Lango-Yaya, Boniface Koffi, Emile Minyaka & Romaric NzoumbouBoko · Microbiology Research Journal International · 2026

Background: Artemisinin-based combination therapies (ACTs) are the cornerstone of malaria treatment. However, partial artemisinin resistance associated with mutations in the Plasmodium falciparum Pfkelch13 propeller domain threatens malaria control efforts. The C580Y substitution...

Open access Research Article 10.9734/mrji/2026/v36i61751