Imine

α-(Imino)pyridyldifluoroethyl Phosphonates: Novel Promising Building Blocks in Synthesis of Biorelevant Aminophosphonic Acids Derivatives

Oksana Shavrina, Lyudmyla Bezgubenko, Andrii Bezdudny, Petro Onys’ko & Yuliya Rassukana · Organics · 2021

A convenient synthetic approach to previously unknown NH-iminophosphonates bearing 2-, 3-, and 4-pyridyldifluoromethyl groups at the imine carbon atom was developed. The synthetic potential of these novel building blocks was demonstrated by their conversion into highly functional...

Open access Research Article 10.3390/org2020007

The Role of the Catalyst on the Reactivity and Mechanism in the Diels–Alder Cycloaddition Step of the Povarov Reaction for the Synthesis of a Biological Active Quinoline Derivative: Experimental and Theoretical Investigations

Soumia Lamri, Affaf Heddam, Meriem Kara, Wassila Yahia & Abdelmalek Khorief Nacereddine · Organics · 2021

An experimental and theoretical study of the reactivity and mechanism of the non-catalyzed and catalyzed Povarov reaction for the preparation of a 4-ethoxy-2,3,4,4a-tetrahydro-2-phenylquinoline as a biological active quinoline derivative has been performed. The optimization of ex...

Open access Research Article 10.3390/org2010006