drug discovery

Indole-Based Macrocyclization by Metal-Catalyzed Approaches

Subba Rao Cheekatla, Debashis Barik, Geethanjali Anand, Rakhi Mol K. M. & Mintu Porel · Organics · 2023

This review is dedicated to the different varieties of macrocycles synthesis bearing indole units in their architecture by metal-catalyzed strategies. The progress of the new macrocyclization approaches is persisted be a keen area of research. Macrocycles contain a wide variety o...

Open access Research Article 10.3390/org4030026

Analyzing Different Acetyl Co-A Metabolizing Enzymes as Potential Drug Targets against Mycobacterium tuberculosis

Shamim Akhtar, Sheetal Singh, Santosh Kumar & Dhiman Sarkar · Microbiology Research Journal International · 2015

Mycobacterium tuberculosis, the causative agent of tuberculosis, is responsible for the deaths of million people around the globe. The scenario is worse than ever due to the emergence of drug resistant strains which are widely spread throughout the globe in much faster ways. To c...

Open access Research Article 10.9734/BMRJ/2015/19032