Aim: Leukemia has been linked to mRNA expression of Sphingosine-1-phosphate receptor-1(S1PR-1) and considering multiple reports on the roles of phytochemicals in Hydrocotyle verticillata and Laportea aestuans, this study aims to evaluate the effects of administration of ethanol e...
Squamous cell carcinomas (SCC) of the oral cavity and the upper aerodigestive tract are mostly associated with tobacco and alcohol consumption. However, a small minority of patients with SCC do not consume tobacco or alcohol. The underlying etiology of head and neck cancer in thi...
Determining Maximum Recommended Starting Dose (MRSD) in first in human (FIH) studies is a crucial milestone in the development path of a new pharmaceutical drug. It is imperative to determine what is the safe starting dose in these trials, as the drug would be introduced for test...
A case of thyroid follicular carcinoma with distant metastasis to the calvaria at initial presentation and its management in a resource-constrained environment. A 69-year-old woman who presented with an anterior neck mass, scalp swelling and right eye proptosis and was diagnosed...
Desmoplastic small round cell tumour is a very rare, highly malignant abdominal neoplasm of mesenchymal origin. Its non-specific symptoms at presentation and poor prognosis with a five year survival rate of 15% despite treatment make it a big challenge to manage. We wish to discu...
Sumanta Bhattacharya, Rituparna Mazumder, Swarupananda Mukherjee & Sparsha Moni Chatterjee·Asian Oncology Research Journal·2021
With the application of nanomedicine for herbal medicines, it can be developed into nano herbal meditation with high bioavailability characteristics and provide a pathway of new research in herbal drug delivery mechanisms. But the major challenge was its low absorption because of...
Background: Prostate cancer is the most commonly diagnosed cancer in men and the second leading cause of cancer mortality after lung cancer worldwide. The incidence of this disease is high among men of African descent. The modes of presentation of patients with prostate cancer ar...
Aims: Gastric metastases are a rare event in the natural history of breast cancer. Report of the Case: We report the case of a gastric metastasis occurred 14 years after initial treatment for breast carcinoma. Discussion: Gastric metastases don’t exceed 0,3% of all metastases. Di...
Aim: To describe an unusual case of colorectal cancer with metastases to various extra-abdominal sites, including subcutaneous tissues as an extremely rare clinical event with 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) findings. Prese...
Fatma Elloumi, Lilia Ghorbal, Mayada Bourmeche, Ahmed Bebou, Hanene Ben Salah & Jamel Daoud·Asian Oncology Research Journal·2021
Non small cells carcinoma represents the most frequent histological subtype in lung cancers. We report, through a review of literature, the indications of radiotherapy in patients presenting with non metastatic lung non small cell carcinoma. Postoperative radiotherapy seemed to i...
Herniation of bladder mucosa through the bladder wall muscle layer is known as bladder diverticulum. The incidence of bladder diverticulum is 1 to 7% of the urinary bladder. About 0.8 to 10% of the urinary bladder diverticula develop carcinoma. Transitional cell carcinoma is the...
Aims: Mucinous carcinomas of breast are rare malignant tumors characterized by mucin-producing cancer cells. Primarily based on cellularity these are divided into two different variants: pure and mixed. The reported incidence of mixed type mucinous breast carcinoma is very less....
The study reporting a case of a 78 year old elderly male patient with multiple co-morbidities with poor performance status with advanced oro-mandibular cancer who underwent oncological resection followed by reconstruction with bi-paddle PMMC flap as an alternative to micro-vascu...
Presence of multiple primary cancers in a single patient with different histopathological entities is an rare occurrence. Here we are reporting a case of 80 year old male diagnosed as malignant melanoma with metachronous primary squamous cell carcinoma of laryngopharynx.
Ehab Tousson, Afaf El-Atrash, Ibrahim El Tantawy El Sayed, Ezar Hafez, Hebat Allah El Basyouny & Ramadan M. Kandyel·Asian Oncology Research Journal·2021
Background and Objective: The study aims to evaluate the protective activity of 9-Diaminoacridine (N1-(acridin-9-yl) propane-1, 3-diamine hydrochloride; 9-DAAD) against Ehrlich Ascites Carcinoma (EAC) bearing mice. Materials and Methods: A total forty mice were randomly divided i...