Background: There is a multitude of problems encountered during the management of critical conditions in low-resource settings. Reducing the administration of brachytherapy from 3 to 2 fractions will assist cervical cancer patients by decreasing the treatment costs and as well as...
Open access
Research Article10.9734/aorj/2025/v8i1105
The dynamic interaction between cancer stem cells (CSCs) and the tumor microenvironment (TME) is increasingly recognized as a key driver of tumor progression, metastasis, and therapeutic resistance. Disrupting this molecular crosstalk offers a promising strategy to improve cancer...
Open access
Research Article10.9734/aorj/2025/v8i1104
Aims: This study aims to identify non-toxic, flavonoid-derived phytochemicals as potential inhibitors of Matrix Metalloproteinase-1 (MMP-1), a key enzyme involved in breast cancer invasion and metastasis. Study Design: An integrative in silico approach was adopted, incorporating...
Open access
Research Article10.9734/aorj/2025/v8i1103
This is hospital based descriptive retrospective case study conducted in isotope hospital in Khartoum state, during the period from March 2019 to June 2019. The study aimed to detect the expression Cytokeratin 5/6 and Smooth Muscle Actin in Triple Negative breast carcinoma tumo...
Open access
Research Article10.9734/aorj/2025/v8i1102
B. Sunjidmaa, Dylan Treger, Xiaoxiao Jia, Jessica Hui, Taivanbat Ganbaatar, Bat-erdene Ganbaatar, Zhaohui Ma & Mizhou Hui·Asian Oncology Research Journal·2025
Background: Advanced lung cancer and its associated pain symptoms place a significant burden on patients. A 35 kDa hyaluronan fragment (HA35) has been confirmed to effectively alleviate inflammatory and neuropathic pain in palliative care settings. This single-arm, prospective pi...
Open access
Research Article10.9734/aorj/2025/v8i1101
Aims: Carotid body tumors (CBTs) are rare, non-chromaffin paragangliomas that typically require surgical resection. However, recurrent cases pose significant challenges. This report describes the successful management of a recurrent CBT with external beam radiotherapy (EBRT), hig...
Open access
Research Article10.9734/aorj/2025/v8i1100
Niragh Sikdar, Brahma Kumar Bhattacharyya, Megha Mahida, Sanskruti Shailesh Rathod, Krithi Pichiah John & Anushka Baidya·Asian Oncology Research Journal·2025
The rare form of thymic cancer demonstrates high aggressiveness in its behavior. A 55-year-old male patient with stage III thymic carcinoma received extensive surgical treatment followed by cisplatin-etoposide chemotherapy. The patient received optimal treatment from three medica...
Open access
Research Article10.9734/aorj/2025/v8i199
Palliative radiotherapy relieves distressing symptoms and helps to manage localized tumor growth when curative treatment is not possible. The study aims to determine that a palliative regimen of 24 Gy in 4 fractions in 4 weeks, once weekly fractionation can achieve a similar resp...
Open access
Research Article10.9734/aorj/2025/v8i198
Cancer resistance to conventional therapies remains a significant challenge in oncology, leading to treatment failure and poor patient outcomes. Immunotherapy has emerged as a promising approach to overcome resistance by harnessing the body's immune system to recognize and elimin...
Open access
Research Article10.9734/aorj/2025/v8i197
Oral and maxillofacial cancers (OMC) remain a significant global public health concern due to their high incidence, mortality rates, and long-term morbidity. Key risk factors, including tobacco use, alcohol consumption, betel quid chewing, and human papillomavirus (HPV) infection...
Open access
Research Article10.9734/aorj/2024/v7i195
Solid tumors, which include malignancies such as breast, lung, prostate, and colorectal cancers, continue to be a leading cause of morbidity and mortality worldwide. Recent decades have witnessed significant advancements in understanding the molecular and cellular mechanisms unde...
Open access
Research Article10.9734/aorj/2024/v7i196
Tumor drug resistance remains a significant challenge in cancer therapy, leading to treatment failure and disease progression. Understanding the mechanisms underlying drug resistance is crucial for developing effective strategies to overcome it. This review discusses the recent a...
Open access
Research Article10.9734/aorj/2024/v7i194
Introduction: Glioma, a prevalent primary brain malignancy, involves multiple signaling pathways crucial for its progression. This study aimed to investigate the clinical significance of Notch1 in patients with glioma, particularly the most common, Astrocytoma tumors. Methods and...
Open access
Research Article10.9734/aorj/2024/v7i193
Muhammad Abdullah-Al-Noman, Golam Mohiuddin Faruque, Mousumi Mallica, Shaiful Hassan Shameem, Shuvra Debnath, Kamrun Nahar Tania, S. K. M. Rasel, Md. Golam Zel Asmaul Husna, Saiful Alam & Tasnim Mahmud·Asian Oncology Research Journal·2024
Background: In Bangladesh, cervical cancer is one of the most prevalent cancers. The current study was conducted to compare the short term effectiveness and acute toxicities of hypofractionated radiotherapy (45 Gy in 18 fractions) with conventional fractionated radiotherapy (50 G...
Open access
Research Article10.9734/aorj/2024/v7i192
Aim: Synovial sarcoma is a malignant tumor of mesenchymal origin. It is more commonly associated with extremities in young adults. The head and neck region account for less than 10% of presentations. The larynx is an extremely rare site. We report a case of a 28-year-old male tre...