Chemotherapy-induced peripheral neuropathy (CIPN) is a frequent and clinically significant adverse effect associated with several commonly used chemotherapeutic agents, including platinum compounds, taxanes, vinca alkaloids, and proteasome inhibitors (Cavaletti and Marmiroli, 201...
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Research Article10.9734/ajorrin/2026/v9i1167
Rajagiri Triveni, Koppula Sirisha, Lingineni Mani Deepa Chandrika, Nalam Vineela Nirmala, Singuluri Monica, Motupalli Poojitha & Konagala Arudra·Asian Journal of Research and Reports in Neurology·2026
Cauda Equina Syndrome (CES) is a very unusual and highly critical emergency in surgery, which is a result of the compression of nerve roots in the lumbar-spinal region and the thalamus, which could have irreversible neurological impairments in case it is not addressed in due time...
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Research Article10.9734/ajorrin/2026/v9i1165
Aims: To emphasize the diagnostic challenge of primary cervical medulloblastoma mimicking a nerve sheath tumor in pediatric patients. Case Report: An 8-year-old boy presented with posterior neck swelling and spastic quadriparesis. MRI revealed a well-defined intradural extramedul...
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Research Article10.9734/ajorrin/2026/v9i1164
Background: Charcot–Marie–Tooth disease type II (CMT2) is an inherited axonal sensorimotor neuropathy with heterogeneous and often subtle manifestations in early childhood. Delayed recognition may limit opportunities for timely preventive rehabilitation and early functional optim...
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Research Article10.9734/ajorrin/2026/v9i1163
Aims: This systematic review aimed to critically evaluate the influence of post-translational modifications (PTMs) on α-synuclein structure, aggregation, and toxicity, and to clarify their relevance to the pathogenesis of Parkinson’s disease, dementia with Lewy bodies, and multip...
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Research Article10.9734/ajorrin/2026/v9i1162
Background: Glioblastoma Multiforme (GBM) presents significant diagnostic and therapeutic challenges due to its complex molecular pathogenesis. Current diagnostic methods often fail to detect early molecular signatures critical for timely intervention. This study integrates micro...
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Research Article10.9734/ajorrin/2025/v9i1161
Introduction: Precision neurorehabilitation represents a fundamental paradigm shift away from standardized, protocol-driven treatment toward dynamically adaptive therapies tailored to the unique biological and functional profiles of individual patients. The recognized high degree...
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Research Article10.9734/ajorrin/2025/v8i1160
Background: Osmotic Demyelination Syndrome (ODS) is a rare neurological disorder typically linked to rapid correction of hyponatremia, but its occurrence due to hypernatremia, especially in the postpartum period, is exceedingly uncommon. Case Presentation: A 23-year-old woman, 14...
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Research Article10.9734/ajorrin/2025/v8i1159
Aim: Investigate the neuroprotective effects of ethanolic extract of Aloe vera (EEAV) on mercury chloride-induced damage in the amygdala and hippocampus of adult male Wistar rats, using histological and molecular docking approaches. Study Design: 35 rats were randomly assigned in...
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Research Article10.9734/ajorrin/2025/v8i1158
Aim: Cerebral palsy (CP) remains the most common cause of chronic childhood disability worldwide. In Nigeria, there is a need to provide updated information to establish current clinical trends. This study described the clinical characteristics of children diagnosed with cerebral...
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Research Article10.9734/ajorrin/2025/v8i1157
Objective: To gather clinicians' perspectives on the clinical use of the combination therapy of pregabalin and nortriptyline for neuropathic pain in Indian settings. Methodology: This cross-sectional study utilized a multiple-response questionnaire comprising 23 questions designe...
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Research Article10.9734/ajorrin/2025/v8i1156
Background: Albinism, a genetically inherited condition characterised by the partial or complete absence of melanin, remains poorly understood and stigmatised in many African societies, including Nigeria. Individuals with albinism often experience discrimination, social exclusion...
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Research Article10.9734/ajorrin/2025/v8i1155
Background: Substance use has become a significant public health issue, particularly among the youth population, with 1 in 20 to 1 in 5 people aged 15 years and above reported to be involved in substance use. This has been linked with several factors, including socio-economic an...
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Research Article10.9734/ajorrin/2025/v8i1154
Background: Hallervorden-Spatz Disease (HSD), an aggressive and rare form of Neurodegeneration with Brain Iron Accumulation (NBIA), has specific rehabilitation issues in its rapid neurodegenerative course and early loss of motor milestones. Physiotherapy literature still lacks th...
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Research Article10.9734/ajorrin/2025/v8i1153
Introduction: Hemangiomas are vascular tumors that are not malignant and arise from the aberrant growth of blood vessels. Primary CNS tumors can occur in any part of the central nervous system, including the brain and spinal cord Aim: The aim of this case report is to emphasize t...
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Research Article10.9734/ajorrin/2025/v8i1152