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All published articles 475

Strengthening the Annual Action Planning Process in Ministry of Health, Sri Lanka: A Case Study of Process Evaluation and Improvement Strategies

T. W. A. N. Thotagamuwa, S. Sasikumar & B. Maithily · Asian Journal of Medical Principles and Clinical Practice · 2026

Annual Action Plans are central management instruments for translating national health policies and strategic priorities into operational activities. This study evaluated the Annual Action Planning process in selected units of Sri Lanka’s Ministry of Health, identified operationa...

Open access Research Article 10.9734/ajmpcp/2026/v9i2477

Continuous Versus Intermittent Propofol for Maintenance of General Anesthesia: Effects on Hemodynamic Stability and Recovery Profile

Ujjwal Basnet, Aashish Dhital, Manju Maharjan & Shubhash Regmi · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: Propofol is commonly used for maintenance of General Anesthesia (GA) and it can be used as Continuous Infusion (CI) or Intermittent Bolus (IB). The optimal or best method is still debated. This study compared the effects of CI and IB propofol on hemodynamic stability,...

Open access Research Article 10.9734/ajmpcp/2026/v9i2476

Drug-Induced Immunomodulation and Healthcare-Associated Infection Risk in Nigerian Trauma Intensive Care Units: A Narrative Review

Oyeleke Stevens Olaide, Adebayo Adekunle, Ikotun Oluwafunmilayo & Oladokun David · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: Critically ill trauma patients in Nigerian intensive care units (ICUs) face a disproportionate burden of healthcare-associated infections (HAIs). While trauma-induced immune dysregulation is well documented, the additional immunomodulatory contribution of routine ICU...

Open access Research Article 10.9734/ajmpcp/2026/v9i2475

Mortality and Case Fatality Rate of Diarrhea Disease among Children under Five Years in Jalingo Lga of Taraba State

D. A. Wanmi, D. G. W. Chintem, L. Luka, C. O. Albert & F. B. A. Destiny · Asian Journal of Medical Principles and Clinical Practice · 2026

Diarrhoeal disease remains a leading cause of morbidity and mortality among children younger than five years, particularly in low- and middle-income countries. This study assessed mortality and the case fatality rate associated with diarrhoeal disease among children younger than...

Open access Research Article 10.9734/ajmpcp/2026/v9i2473

Serum PSA Levels and VDR Gene-Environment Interaction in Sudanese Men with Prostate Cancer: Role of BsmI Polymorphism (rs1544410)

Asma Jaafar Oshaik Mohammed, Mohamed Osman Ali, Abdelhakam G. Tamomh, Ahmed Ibn Edriss & Kamaleldin Abdelmakrim Abdalla · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: BsmI is a 3'UTR VDR variant that may affect mRNA stability. Its association with prostate cancer (PCa) has been inconsistent across ethnic groups. Objective: The study aims to evaluate the association of the BsmI genotype and alleles with PCa risk and PSA levels in Su...

Open access Research Article 10.9734/ajmpcp/2026/v9i2474

Methotrexate-associated Demyelinating Leukoencephalopathy after Low-dose Oral Therapy in a Patient with Post-viral Polyarthralgia

Singireddy Dattakshaya, Kollipara Lakshmi Srivalli, Kattepogu Hansitha, Devara Gowri Priya, Banavath Durga Bhavani & Tata Leela Ram Gopal · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: Methotrexate is a widely used disease-modifying antirheumatic drug. Neurological toxicity is uncommon, particularly after short-term, low-dose oral treatment, and may resemble acute cerebrovascular disease. Case Presentation: A 44-year-old woman receiving oral methotr...

Open access Research Article 10.9734/ajmpcp/2026/v9i2472

Quality of Inpatient Clinical Documentation: A Bed Head Ticket Audit at a Tertiary Care Hospital in Sri Lanka

U. G. Gihan Chaminda, K. W. R. Wimalagunarathne & G. Paul Roshan · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: Clinical documentation is a cornerstone of quality healthcare and patient safety. The accuracy and completeness of patient records are essential for effective clinical decision-making and continuity of care. The Bed Head Ticket (BHT) serves as the principal medical re...

Open access Research Article 10.9734/ajmpcp/2026/v9i2471

Headache Burden, Healthcare-seeking Behaviour and Self-referral Practices among Secondary School Teachers in Ekiti State, Nigeria

O. A. Dada, M. O. Adetoye, M. B. Yusuf & A. I. Okunlola · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: Headache disorders are among the leading causes of disability worldwide and contribute substantially to reduced quality of life, impaired work productivity, and increased healthcare utilisation. Despite their high burden, many individuals rely on self-medication or de...

Open access Research Article 10.9734/ajmpcp/2026/v9i2470

Evaluating the Impact of the Malaria Vaccine Rollout on Malaria Morbidity Among Under-Five Children in Phase 1 MVIP Districts in Oti Region, Ghana

Williams Agbesi, William Kwame Witt, Paulina Nneka Adoba, Solomon Wussah, Collins Brafo & Prince Kwadwo Gyasi · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: Sub-Saharan African (SSA) countries remain disproportionately affected by malaria. To address the persistently high incidence, novel therapeutic interventions, such as the malaria vaccine, have been introduced in four pilot countries in SSA, including Ghana. Objective...

Open access Research Article 10.9734/ajmpcp/2026/v9i2468

Safeguarding Data and Building Trust in Technology-Enabled Rehabilitation Counseling: A Review of Governance Models for Fair and Accessible Care

Cornelia Ifeoma Ejoh · Asian Journal of Medical Principles and Clinical Practice · 2026

Technology-enabled rehabilitation counselling, encompassing telerehabilitation, digital case management, wearable-based self-tracking, and artificial intelligence (AI) decision support, has expanded access to vocational and psychosocial rehabilitation while simultaneously increas...

Open access Research Article 10.9734/ajmpcp/2026/v9i2469

Gender-based Experiences of People Living with HIV in Owerri North Local Government Area of Imo State, Nigeria

J. C. Achoronye, M. C. Ezeama, P. O. Chinedu-Eleonu, C. N. Nwadike & U. E. Agubuo · Asian Journal of Medical Principles and Clinical Practice · 2026

Nigeria continues to carry a substantial HIV burden, yet gender-related differences in the lived experiences of people living with HIV remain insufficiently examined at local levels. This study assessed gender-based experiences among adults living with HIV in Owerri North Local G...

Open access Research Article 10.9734/ajmpcp/2026/v9i2467

Effect of Sociodemographic Factors on Uptake of Intermittent Preventive Treatment for Malaria at Antenatal Clinics at Primary Health Centers in Orlu Zone, Nigeria

V. I. Ogoke, K. O. Obasi, I. F. Eberendu, P. O. Chinedu-Eleonu, D. Onyemekara, U. E. Agubuo & C. N. Nwadike · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: Intermittent preventive treatment in pregnancy with sulphadoxine-pyrimethamine (IPTp-SP) reduces malaria-related risks, but completion of the recommended dosing schedule remains suboptimal. Aim: This study assessed the influence of sociodemographic factors on IPTp-SP...

Open access Research Article 10.9734/ajmpcp/2026/v9i2466

Adoptive Cellular Immunotherapy in Glioblastoma: Mechanistic Insights, Clinical Progress, and Future Directions of CAR-T and TIL Therapies

Alper DEMIREZEN & Gizem Nur Mutlu · Asian Journal of Medical Principles and Clinical Practice · 2026

Glioblastoma remains the most common and lethal primary malignant brain tumour in adults, and outcomes have changed little despite maximal surgical resection, radiotherapy and temozolomide chemotherapy. Adoptive cellular immunotherapy, principally chimeric antigen receptor T-cell...

Open access Research Article 10.9734/ajmpcp/2026/v9i2464

Proprioceptive Deficits in Cervicogenic Headache: An Open-Source-Verified Systematic Review

Radhika Sinha & Prerna Mohan Saxena · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: Cervicogenic headache is a secondary headache disorder attributed to cervical spine or cervical soft-tissue dysfunction. Cervical proprioceptive impairment has been proposed as one mechanism linking neck pain, impaired head-neck orientation, dizziness, postural instab...

Open access Research Article 10.9734/ajmpcp/2026/v9i2465

Lifestyle and Reproductive Risk Factors Associated with Cervical Dysplasia among Women in Rivers State, Nigeria

Ikukaiwe, Juliet Nkechi, B. E. B. Nkwoke & P. O. Chinedu-Eleonu · Asian Journal of Medical Principles and Clinical Practice · 2026

Background: Cervical dysplasia remains an important preventable precursor of cervical cancer, particularly in low- and middle-income settings where screening uptake, early detection, and follow-up care remain uneven. Lifestyle behaviours and reproductive exposures may contribute...

Open access Research Article 10.9734/ajmpcp/2026/v9i2463