Godiya Peter Mamman, Caleb Ndako Angulu, Aminu, Ado, Mohammed Evuti Mahmud, Ruqayyatu Aliyu, Samuel Angulu & Adeoye Daniel Owoyale·Asian Journal of Immunology·2025
The field of metabolomics involves the high-throughput identification and measurement of all endogenous and exogenous low-molecular-weight (<1kDa) small molecules or metabolites in a biological system by analyzing the metabolome in cells, biofluids, tissues, or organisms. Meta...
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Research Article10.9734/aji/2025/v8i1171
Background: Immune tolerance is established between the foetus and the mother in normal pregnancies. However, this tolerance may be breached, resulting in undesired pregnancy outcomes such as spontaneous abortion, foetal anomalies, and maternal complications. Reported studies sug...
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Research Article10.9734/aji/2025/v8i1170
Background: The cat-pork syndrome and the cross-reactivity between cat dander and dog dander are particular situations associated with the allergic multimorbidity phenotypes. The perception of this cross-reactivity must benefit the allergist dealing with these conditions. Aim: To...
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Research Article10.9734/aji/2025/v8i1168
Background: Panallergens, such as tropomyosin, produce cross-reactivity between indoor allergens and food allergens, including the house dust mite Blomia tropicalis and the Brazilian pink shrimp Farfantepenaeus brasiliensis, and are responsible for the clinical symptoms present i...
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Research Article10.9734/aji/2025/v8i1169
Post-operative wound infections (POWIs), sometimes referred to as post-surgical wound infections (PSWIs), are a common complication following surgery. Surgeries frequently elicit a variety of immunological responses subsequent to tissue damage and incision which may hinder wound...
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Research Article10.9734/aji/2025/v8i1167
Monocytes and macrophages play a pivotal role in the pathogenesis of HIV infection, contributing not only to viral persistence but also to the development of non-AIDS-defining events (nADEs) in People Living with HIV (PLWH). These innate immune cells act as long-lived viral reser...
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Research Article10.9734/aji/2025/v8i1166
Inflammatory bowel diseases (IBD) are increasingly common pathologies, affecting both adults and children. This study investigates the clinical and epidemiological characteristics of IBD among patients at the gastroentero-hepatology department of Annaba University Hospital. Condu...
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Research Article10.9734/aji/2025/v8i1165
Okolie Lucy Janefrancis, Maduka Amuche Stella, Ojeniran Taiwo Paul, Yahaya Imran Umar, Lawal Mustapha, Oniye Mariam Masud & Umar Muhammad Muhsin·Asian Journal of Immunology·2025
Trained immunity, a concept introduced more than a decade ago, defines the non-specific memory capacity of innate immunity by epigenetic and metabolic reprogramming. It involves features of epigenetic and metabolic reprogramming of innate immune cells that induce long-term functi...
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Research Article10.9734/aji/2025/v8i1163
Immune mediated diseases and syndromes are rare and attributed at most to genetic and environmental interactions. Macrophagic Myofasciitis MMF is one of these syndromes sub-entities. In the present opinion the immunobiology of MMF was being reviewed. The molecular autoimmune mech...
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Research Article10.9734/aji/2025/v8i1164
Anti-N antibodies usually possess cold-reactive properties which make them clinically insignificant and are mostly classified as naturally occurring IgM antibodies. These antibodies sometimes trigger reactions at body temperature (37°C) or in the anti-human globulin phase resulti...
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Research Article10.9734/aji/2025/v8i1162
Background: Several publications report that formaldehyde is responsible for hypersensitivity reactions in patients with contact dermatitis, as diagnosed by "in vivo" provocation tests. There is no standardized lab exam that can endotype the mechanisms responsible for these pheno...
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Research Article10.9734/aji/2025/v8i1161
The aim of the study was to determine the prevalence of myocardial and circulatory complications among lupus patients, such as pericarditis, heart failure, endocarditis, ventricular dysfunction, and Myocarditis. It was also to assess the association of lupus with increased myocar...
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Research Article10.9734/aji/2025/v8i1160
Background: Human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) remain major health problems worldwide, with high mortality and morbidity rates, particularly in developing countries. The United Nations Programme on HIV/AIDS (UNAIDS) reported that ther...
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Research Article10.9734/aji/2025/v8i1159
Background: Cocoa is one of the foods more consistently associated with high nickel content, a metal that functions as a hapten responsible for various non–IgE-mediated symptomatic hypersensitivities. Aim: The present study is a proof-of-concept that hypothesizes that LAIT and th...
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Research Article10.9734/aji/2025/v8i1158
There is a mutual bidirectional cross-talk between mammalian microbiomes MM and their respective immune systems during the host homeostatic and disease states, the microbiome- immune axis. The objective of the present opinion paper was to map the current status of the microbiome-...
Open access
Research Article10.9734/aji/2025/v8i1157