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All published articles 281

Uncommon Presentation of Hodgkin’s Lymphoma: A Case Report

C. E. Nonyelu, A. J. Madu, I. O. Anigbogu & O. C. Okafor · Asian Hematology Research Journal · 2021

Hodgkin’s lymphoma is a lymphoid malignancy that rarely presents with extranodal involvement and even rarer is presentation involving the central nervous system (CNS). The index patient had a diagnosis of Hodgkin’s lymphoma made from histology and immunophenotyping of the cervica...

Open access Research Article

Management of Severe Aplastic Anaemia in a Jehovah’s Witness patient: The challenge and Lessons

Nelson I. Oguanobi, Augustine N. Duru, Paul C. Okorie & Amobi O. Egwuonwu · Asian Hematology Research Journal · 2021

Aplastic anaemia is a life threatening consequence of severe bone marrow failure often requiring supportive care with component blood transfusions and stem cell replacement procedures. In this case report and review of literature, the authors highlight peculiar challenges in the...

Open access Research Article

Multiple Myeloma: An In-depth Review of the Historical and Pathogenetic Processes

Anazoeze Jude Madu, Charles Nonyelu, Helen Chioma Okoye & Sunday Ocheni · Asian Hematology Research Journal · 2021

Myeloma is a plasma cell disorder which occurs with varying prevalence across different populations across the globe. Knowledge of the disease pathogenesis as well as its diagnosis and treatment has evolved over the years. The mutations that underlying the progression from benign...

Open access Research Article

Role of Taurine in Children with Anaemia

Arif A. Faruqui · Asian Hematology Research Journal · 2021

Iron deficiency (ID) is the most common health problem noted in paediatric population. The prevalence of anaemia in India among paediatric group is 23.5% in 5-7 years and 58.7% in children below 5 years. The major cause of ID in children is low intake of iron from the actual requ...

Open access Research Article

Validation of Manufacturers Recommended Working Volumes of Fluorochrome-conjugated Monoclonal Antibodies for Flowcytometric Analysis of Lymphocytes

Moses Dabah Lugos, Gwom Irimiya Davou, Tabitha Silas Vem, Venkateswarlu Perikala & Obadiah Dapus Damulak · Asian Hematology Research Journal · 2021

Background: Flow cytometry is a robust and rapidly growing technique used to analyse multiple parameters concurrently on a single cell basis. Cell populations can be characterised using a combination of both surface and intracellular antigens. The act of generating the best resea...

Open access Research Article

Profile of Autoimmune Haemolytic Anaemia: Analysis of 10 Years Data from a Hematology Center in Eastern India

Avriti Baveja, Prakas Kumar Mandal, Arnab Chattopadhyay, Malini Garg, Prakash Singh Shekhawat & Tuphan Kanti Dolai · Asian Hematology Research Journal · 2021

Aims: To study the Clinico-haematological profile and therapy outcome of patients with autoimmune haemolytic anaemia (AIHA) Study Design: Retrospective analysis through the case records of 69 patient treated at the Department of Hematology, NRS Medical College, Kolkata over a per...

Open access Research Article

Acute Promyelocytic Leukemia: A Decade Long Experience with Evolving Treatment Strategies

Prakash Singh Shekhawat, Prakas Kumar Mandal, Malini Garg, Avriti Baveja & Tuphan Kanti Dolai · Asian Hematology Research Journal · 2021

Aims: To study the characteristics and outcome of Acute promyelocytic leukemia (APL) patients. Study Design: Retrospective analysis of APL patients (n=106) treated at the Department of Hematology, NRS Medical College, Kolkata over a period of more than 10 years from October 2009...

Open access Research Article

Manual Exchange Blood Transfusion with Cytoreduction in the Management of Chronic Myelocytic Leukemia with Hyperleukocytosis: A Case Report

Ayuba Zakari, Ezra Danjuma Jatau, Adeyemi Ayobola Olusegun, Akor Akoyi Emmanuel & Dauda Yohanna Bangalu · Asian Hematology Research Journal · 2021

Chronic Myelocytic Leukaemia (CML) is a haematological malignancy characterized by granulocytic leukocytosis, splenomegaly, and weight loss. Hyperleukocytosis can lead to leukostasis and hyperviscosity syndrome. Leukapheresis is used to manage hyperleukocytosis, but apheresis mac...

Open access Research Article

The Relation between Glutathione S Transferase (GSTM1, GSTP1 and GSTT1) Polymorphisms and Clinical Diversity of Sickle Cell Disease among Pediatric Sudanese Patients

Naif Taleb Ali, Ozaz Yagoup Mohammed Ahmed, Fayad Osman Mohammed & Huda Mohammed Haroun · Asian Hematology Research Journal · 2021

Background: Sickle cell disease (SCD) is a highly variable condition, with some patients being asymptomatic and others frequently admitted to hospital. Impairment of the glutathione system due to genetic polymorphisms of glutathione S-transferase (GST) genes is expected to influe...

Open access Research Article 10.9734/ahrj/2021/v4i278

Piperacillin Induced Acute Severe Thrombocytopenia during VV ECMO in COVID19 Pneumonia: Case Report and Review of the Literature

Mohammed K. O. Qandil, Hussam Abdel Rahman S. AL Soub & Tasleem Raza N. Mohd · Asian Hematology Research Journal · 2021

Piperacillin-tazobactam is a frequently used antibiotic that has a broad spectrum of antibacterial activity and a wide safety profile. The development of thrombocytopenia following the use of piperacillin is usually a gradual phenomenon occurring several days following the first...

Open access Research Article

Comparative Study of Erythrocyte Sedimentation Rate (ESR) three Sampling Techniques: Whole Blood in Tri-Sodium Citrate, Whole Blood in Ethylene Di Amine Tetra Acetic Acid (EDTA) , EDTA Blood Diluted with Tri–Sodium Citrate

H. P. A. Gunathilaka, A. W. G. M Sameera, K. H. B. P Fernandopulle, K. S. Pathirage & R. S. Lokupitiya · Asian Hematology Research Journal · 2021

Background: ESR is a simple, inexpensive test commonly used for screening of infective, inflammatory and neoplastic processes. The recommended standard method for ESR by  the International Committee for Standardization in Hematology(ICSH) is the Westergren method where blood is a...

Open access Research Article

Overview of the Distribution and Presentation of Patients with Sickle Cell Disorders: A Report from a Tertiary Care Centre in Eastern Part of India

Ankita Sen, Tuphan Kanti Dolai & Arnab Chattopadhyay · Asian Hematology Research Journal · 2021

Aims: With globalisation, patients with Sickle cell disorders can be found all over the world. Depending on the original genotype, the disease manifestations vary. This study aimed to assess the distribution and clinical presentation of patients with Sickle homozygous/ heterozygo...

Open access Research Article