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All published articles 94

Facile Photochemical/Thermal Assisted Hydration of Alkynes Catalysed under Aqueous Media by a Chalcogen Stabilized, Robust, Economical, and Reusable Fe3Se2(CO)9 Cluster

Munsaf Ali, Avinash K. Srivastava, Nitinkumar Satyadev Upadhyay, Naveen Satrawala & Raj K. Joshi · Organics · 2023

In this report, the catalytic potential of chalcogen-stabilized iron carbonyl clusters [Fe3E2(CO)9 (E = S, Se, Te)] for the photolytic hydration of alkynes has been explored. The iron chalcogenide clusters bring excellent transformations of terminal and internal alkynes to their...

Open access Research Article 10.3390/org4020020

A Novel Class of Functionally Tuneable Star-Shaped Molecules for Interaction with Multiple Proteins

Debashis Barik, Geethanjali Anand, Subba Rao Cheekatla & Mintu Porel · Organics · 2023

Molecules with tuneable properties are well known for their applications in the material and bio-medical fields; nevertheless, the structural and functional tunability makes them more significant in diverse applications. Herein, we designed and synthesized a novel class of star-s...

Open access Research Article 10.3390/org4020018

The Regio- and Stereoselective Synthesis of 1,4-Diarylbut-1-en-3-ynes Having Aryl Groups at the Mutual Syn Positions

Szymon Rogalski, Natalia Szymaszek & Cezary Pietraszuk · Organics · 2023

(E)-1-aryl-2,4-bis(trimethylsilyl)but-1-en-3-ynes readily undergo protodesilylation and subsequent aerobic, copper-free Sonogashira cross-coupling with aryl halides to form (E)-1,4-diaryl-2-(trimethylsilyl)but-1-en-3-ynes. The proposed one-pot, two-step approach allows access to...

Open access Research Article 10.3390/org4020017

Computational Modeling of the Feasibility of Substituted [1.1.1]Propellane Formation from Anionic Bridgehead Bromide Precursors

Katherine E. Gates, Caitlin Herring, Andrew T. Lumpkin, Robert J. Maraski, Elizabeth G. Perry, Madelen G. Prado, Sarah L. Quigley, Jazmine V. Ridlehoover, Edith Salazar, Kynslei Sims, Kaitlin R. Stephenson, Emma A. Stewart, Mackenzie E. Sullivan, James R. Tucker & Gary W. Breton · Organics · 2023

[1.1.1]Propellane, a compound whose structure includes two saturated carbons in which all four bonds are directed into a single hemisphere, is of theoretical interest, but has also seen recent practical applications. Mono-, di-, and trisubstituted derivatives of this propellane (...

Open access Research Article 10.3390/org4020016

A Reaction of N-Substituted Succinimides with Hydroxylamine as a Novel Approach to the Synthesis of Hydroxamic Acids

Bogdan A. Tretyakov, Svyatoslav Y. Gadomsky & Alexei A. Terentiev · Organics · 2023

We describe a novel two-step approach for the synthesis of compounds with a hydroxyl-amide group (hydroxamic acids), which are widely known for their biological activity (histone deacetylase inhibitors, matrix metalloproteinases inhibitors and others). The first stage is the synt...

Open access Research Article 10.3390/org4020015

Advance in the Synthesis of Sulfoxides and Sulfinamides from β-Sulfinyl Esters

Xianjie Yin, Qiaoling Zhang & Qingle Zeng · Organics · 2023

Sulfoxides and sulfinamides play important roles in the pharmaceutical industry, organic synthesis and fine chemicals. This review will demonstrate that, under catalysis by transition metals, β-sulfinyl esters, as nucleophilic reagents, react with a variety of electrophilic reage...

Open access Research Article 10.3390/org4020014

Exploration of the Divergent Outcomes for the Nenitzescu Reaction of Piperazinone Enaminoesters

Rebecca Hermans, Max Van Hoof, Luc Van Meervelt & Wim Dehaen · Organics · 2023

The Nenitzescu reaction is a condensation reaction between an enamine and a quinone, which can give rise to a wide variety of reaction products depending on the nature of the starting material and the reaction conditions. The most commonly observed products are 5-hydroxyindoles a...

Open access Research Article 10.3390/org4020012

A New Rapid and Specific Iodination Reagent for Phenolic Compounds

Till Hauenschild & Dariush Hinderberger · Organics · 2023

A new rapid iodination reagent, N1,N3,N5-tris[(2,4,6-trimethylpyridine)iodo(I)]-2,4,6-triphenyl-s-triazine trihexafluorophosphate, was synthesized in a modification of the established synthesis of 2,4,6-triiodo-3,5-dimethylphenol in the presence of bis(2,4,6-trimethylpyridine)iod...

Open access Research Article 10.3390/org4020011

Cell Viability Study of ZnCuInS/ZnS–TPPS4 Conjugates against Different Cell Lines as a Promising Fluorescent Probe

Ncediwe Tsolekile, Sundararajan Parani, Thabang Calvin Lebepe, Rodney Maluleke, Vuyelwa Ncapayi, Mangaka Clara Matoetoe, Sandile Phinda Songca & Oluwatobi Samuel Oluwafemi · Organics · 2023

In the present work, we report a simple synthetic strategy for fabricating ZnCuInS/ZnS–TPPS4 conjugates and study its cytotoxicity as a promising material for imaging and phototherapy applications. The quaternary QDs were synthesized using eco-friendly materials such as glutathio...

Open access Research Article 10.3390/org4010010

Triple Benefits of Cardanol as Chain Stopper, Flame Retardant and Reactive Diluent for Greener Alkyd Coating

Maxinne Denis, Cédric Totée, Damien Le Borgne, Rodolphe Sonnier, Sylvain Caillol & Claire Negrell · Organics · 2023

Cardanol, a waste from the food industry and widely produced (1 Mt/y), has been used as a chain stopper during the polycondensation of short oil alkyd resins in order to replace benzoic acid. Then, phosphorylated cardanol has been added in order to both reduce solvent content and...

Open access Research Article 10.3390/org4010009

Looking for a Safe Bridge: Synthesis of P3HT-Bridge-TBO Block-Copolymers and Their Performance in Perovskite Solar Cells

Aleksandra N. Zhivchikova, Irina V. Klimovich, Maxim E. Sideltsev, Aly Elakshar, Artur T. Kapasharov, Alexander V. Akkuratov, Albert G. Nasibulin, Keith J. Stevenson & Marina M. Tepliakova · Organics · 2023

Here, we present a synthesis of three novel conjugated block-copolymers (BCP) with general formula P3HT-bridge-TBO, where P3HT is a poly(3-hexyl)thiophene, TBO is a thiophene-benzothiadiazole block, and the bridge is composed of two fluorene units (FF) or two thiophenes (TT) or a...

Open access Research Article 10.3390/org4010008

Thia-Michael Reaction under Heterogeneous Catalysis

Giovanna Bosica, Roderick Abdilla & Alessio Petrellini · Organics · 2023

Thia-Michael reactions between aliphatic and aromatic thiols and various Michael acceptors were performed under environmentally-friendly solvent-free conditions using Amberlyst® A21 as a recyclable heterogeneous catalyst to efficiently obtain the corresponding adducts in high yie...

Open access Research Article 10.3390/org4010007

Palladium Catalyzed Ring-Opening of Diazabicylic Olefins with 4-Halo-1,3-Dicarbonyl Compounds: Accessing 3(2H)-Furanone-Appended Cyclopentenes

Vishnu K. Omanakuttan, Alisha Valsan, Henning Hopf & Jubi John · Organics · 2023

We have realized a Pd-catalyzed ring-opening of diazabicyclic olefins with 4-halo-1,3-dicarbonyl compounds. This reaction resulted in the formation of 3(2H)-furanone-appended hydrazino cyclopentenes. The reaction proceeds via the formation of a π-allylpalladium intermediate which...

Open access Research Article 10.3390/org4010006