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All published articles 499

Assessment of Renal Function Using Serum Urea and Creatinine in Type 2 Diabetes Mellitus Patients Receiving Care at Referral Hospitals in Enugu, Nigeria

Hector Okechukwu Obianyido, Ozioma Ebere Obianyido & Vivian Chidinma Ikekpeazu · Asian Journal of Research in Biochemistry · 2025

Introduction: Type 2 Diabetes Mellitus (T2DM) often causes renal dysfunction, which may progress to chronic kidney disease. The aim of the study was to assess the renal function of T2DM patients receiving treatment in referral hospitals in Enugu metropolis by measuring their seru...

Open access Research Article 10.9734/ajrb/2025/v15i6452

Evaluation of Lipid Accumulation Product, Visceral Adiposity and Atherogenic Risk Indices in Type 2 Diabetics in Port Harcourt, Nigeria

Ojoye N. Briggs, Abubakar A. Sheudeen & Kemzi N. Elechi-Amadi · Asian Journal of Research in Biochemistry · 2025

Background: This study evaluated lipid accumulation product index (LAPi), visceral adiposity index (VAI), and atherogenic risk indices in diabetics in Port Harcourt, Nigeria. Materials and Methods: A total of 300 subjects comprising 150 diabetic subjects (tests) and 150 non-diabe...

Open access Research Article 10.9734/ajrb/2025/v15i6450

Chemical Characterization of Anthocleista djalonensis A. Chev. and Uvaria chamae P. Beauv. Extracts as Potential Insecticides of Stored Products against Infestation

PHILIP-ATTAH Mary Tejumade, Obembe Olusola Michael, ADEWOYE Bolajoko Bolarinwa, AKINBULUMA Mobolade Dele & OMOTOSO Olumuyiwa Temitope · Asian Journal of Research in Biochemistry · 2025

The bioactive compounds in Anthocleista djalonensis stem bark and Uvaria chamae root bark, through the standard procedures of phytochemical analysis and Gas Chromatography-Mass Spectrometry (GC-MS) analysis, were investigated for 30 days at the Science Technology Laboratory, Ibad...

Open access Research Article 10.9734/ajrb/2025/v15i6449

The Sugar Coated Killer Cryptococcus neoformans: New Insights into Its Polysaccharide Capsule

Forman Erwin Siagian · Asian Journal of Research in Biochemistry · 2025

Aims: To analyze the polysaccharide property of capsular portion belongs to the incidiosa yeast, Cryptococcus neoformans. Discussion:  Cryptococcus neoformans is an encapsulated fungal pathogen that is acquired by human and animal hosts through inhalation of environmental infecti...

Open access Research Article 10.9734/ajrb/2025/v15i6448

Comparative Sub-acute Toxicity Study of Benign Prostatic Hyperplasia-induced Wistar Rats Treated with Ethanol Extracts of Artocarpus heterophyllus Stembark, Leaf, And Pulp

Nwako, C.A., Ene A.C, Nwaogu L.A & Nzebude C.P · Asian Journal of Research in Biochemistry · 2025

Aims: This study investigated the comparative in vivo sub-acute toxicity and biochemical effects of ethanol extracts of A. heterophyllus (stembark, leaf, and pulp) in benign prostatic hyperplasia (BPH)-induced Wistar albino rats. Methodology: A total of fifty-five male rats were...

Open access Research Article 10.9734/ajrb/2025/v15i6446

Antimicrobial Activity of Biosynthesized Silver Nanoparticles from Mentha arvensis and Syzygium aromaticum and Their Combinations with Levofloxacin and Cefotaxime

Okey-Orji V. N, Ngwai Y. B, Nkene I. H, Asogwa, I. S, Usman, T. F, Fagbola, O. F, Akyala, I. A, Igbawua I. N, Galleh, R. P, Tama, S. C, Abdulmumin R. I, Aremu, O. K & Simon, O. A · Asian Journal of Research in Biochemistry · 2025

Aims: This study is aimed at evaluating the antimicrobial activity of biosynthesized silver-nanoparticles (AgNPs) from Mentha arvensis and Syzygium aromaticum and its combinations with cefotaxime and levofloxacin. Study Design:  Cross sectional study. Place and Duration of Study:...

Open access Research Article 10.9734/ajrb/2025/v15i6447

Influence of the Microbes Mediated Organic Production Module on the Yield and Quality of the Khasi Mandarin (Citrus reticulata Blanco) in the Upper Brahmaputra Valley Zone

Buddhisatya Dowarah & Pauline Alila · Asian Journal of Research in Biochemistry · 2025

Aims: To find out the effect of microbes mediated organic production modules on the yield and quality of khasi mandarin. Study Design: Randomised Complete Block Design. Place and Duration of Study: The present field experiment was carried out at Pangna Gaon, Margherita, Tinsukia...

Open access Research Article 10.9734/ajrb/2025/v15i6445

Phytochemical Composition and in vitro Antioxidant Potential of the Ethanolic Extract of Trigonella foenum-graecum (fenugreek) Seeds

Amarachi, Chidinma Chikezie, Okereke, Chukwuma Stanley, Nosiri, Chidi Ijeoma, Aaron, Friday Chinomso, Chibuike, Valentine Edom, Udochukwu, Stanley Alugbuo, Okore, Finian Uchenna & Iwuchukwu, Bruno Obinna · Asian Journal of Research in Biochemistry · 2025

Medicinal plant serves as a natural source of antioxidants that protect against oxidative stress and related pathologies. Trigonella foenum-graecum L. (fenugreek) is a medicinal plant that is known to possess antioxidant and anti-inflammatory properties due to their rich phytoche...

Open access Research Article 10.9734/ajrb/2025/v15i6444

Phytochemical Profiling and Combinatorial-Optimization of Zingiber officinale, Allium sativum and Curcuma longa Extracts for In-vitro \(Fe^{2+}\)-Chelation as Potential Heavy-Metal Detoxifiers

Joshua C. Ezema, Opeyemi D. Omoleye, Joshua O. Kanwanye, Sunday C. Chukwudoruo, Kizito M.E. Iheanacho, Cosmas O. Ujowundu, Favour N. Ujowundu, Linus O. Agwu, Viola A. Onwuliri & Kingsley O. Obasi · Asian Journal of Research in Biochemistry · 2025

This research investigated the bioactive compounds of Zingiber officinale (ginger), Allium sativum (garlic) and Curcuma longa (turmeric) and the combinatorial capacity of the extracts to chelate ferrous (Fe2+) ions. Phytochemicals were determined using gas chromatography-flame io...

Open access Research Article 10.9734/ajrb/2025/v15i6443

Evaluation of Combined Effect of Ocimum gratissimum and Ageratum conyzoides Leaf Powder as a Sustainable Bioinsecticide against Cowpea Weevil

Victor C. Ihebom, Cosmas O. Ujowundu, Callistus I. Iheme, Favour N, Ujowundu, Christopher O. Echereobia, Ngozi U. Nwogwugwu, Adaeze A. Nwakaudu, Margaret N. Ibe, Raymond C. Ibeh, Linus O. Agwu, Kingsley U. Obasi & Emmanuel C. Okwara · Asian Journal of Research in Biochemistry · 2025

This study was conceived to improve the preservation of cowpea grains by eliminating the destruction of cowpea grains by cowpea weevils (Callosohruchus maculates) and to eliminate the detrimental effect of synthetic pesticide on the environment. This study evaluated the proximate...

Open access Research Article 10.9734/ajrb/2025/v15i6442

Antihyperlipidemic Effect of the Combined Extract of Moringa oleifera and Psidium guajava Leaf in Phenylhydrazine-Induced Rats

Orororo, OC, Awhin, EP, Okoro, EO, Ogwuadi, CR & Akachukwu, FP · Asian Journal of Research in Biochemistry · 2025

The lipid profile includes measurements such as total cholesterol (TC), triglycerides (TG), low-density lipoprotein (LDL), and high-density lipoprotein (HDL). Alterations in these parameters are strongly associated with conditions such as atherosclerosis, coronary heart disease,...

Open access Research Article 10.9734/ajrb/2025/v15i5441

Hypolipidemic and Antidiabetic Potential of Hyphaene thebaica leaf Extracts on Stz/Hfd-Induced Diabetic/Hyperlipidemic Wistar Rats

Abdulkarim Abuzaid Hamza, Sambo Ponfa, Murtala Ya’u, Salihu Ibrahim, Yahuza Gimba Muhammad, Muazu Alkali Adamu, Dungum Domnan, Alhassan Jibrin & Affiong Bassey Nsa · Asian Journal of Research in Biochemistry · 2025

Diabetes mellitus, a global metabolic disorder arising from issues with insulin secretion or action, has led to the exploration of plant-derived products for safe and effective antidiabetic solutions. Hyphaene thebaica, a desert palm native to the Nile Valley, sub-Saharan Africa,...

Open access Research Article 10.9734/ajrb/2025/v15i5439

Phytochemical, Antioxidant and Free Radical Scavenging Activities of Ethanol Extract of Costus afer, Sida acuta and Irvingia gabonensis

Chioma Juliet Ejiofor, Adamma Angela Emejulu, Chieme Sunday Chukwudoruo, Chibuike Valentine Edom, Muhammad Tasi'u Uba & Nnenna Chinenyenwa Osuji-kalu · Asian Journal of Research in Biochemistry · 2025

Background: Scientific investigation supporting the use of various African plant species for the management of diseases, including neurological disease is currently ongoing. Plant-based antioxidants have recently received a lot of attention because of their purported positive imp...

Open access Research Article 10.9734/ajrb/2025/v15i5440

HPLC Analysis of Bioactive Constituents and in vitro Antidiabetic Potential of Ethanolic Leaf Extract of Solanum aethiopicum

Happiness Adaekwu Orlu, Christopher Unyime Ebong, Ajoko Imomotimi Timipa, Return Overe & Ebubechukwu C. EZEONWUMELU · Asian Journal of Research in Biochemistry · 2025

Solanum aethiopicum (African garden egg) is a tropical vegetable commonly consumed in Nigeria and other parts of Africa, traditionally used not only as food but also in folk medicine for the management of chronic ailments such as diabetes. This study aimed to investigate the phyt...

Open access Research Article 10.9734/ajrb/2025/v15i5437

Quantitative Phytochemical Profiling, Nutritional Composition and Antioxidant Activity of Carica papaya (paw-paw) Leaves

Obiajulu Christian Ezeigwe, Chiamaka Vivian Okochi, Ngozichukwuka Immaculata Achara, Nma Helen Ifedilichukwu, Chiamaka Maryann Nwarienne & Miracle Oluebubechukwu Mbidom. · Asian Journal of Research in Biochemistry · 2025

Introduction: Carica papaya commonly known as pawpaw is a rich medicinal plant with high nutritional value. This study focused on assessing the phytochemical composition, proximate analysis, and in vitro antioxidant activities of the leaves of Carica papaya to unravel its potenti...

Open access Research Article 10.9734/ajrb/2025/v15i5438