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All published articles 499

Evaluation of Haematological Parameters in Stroke Patients in South-Western Nigeria

I. Akinlua & M. F. Asaolu · Asian Journal of Research in Biochemistry · 2019

Introduction: Stroke is a leading cause of morbidity and mortality worldwide. Atherosclerosis is a leading cause of both ischemic and haemorrhagic stroke which has been linked to chronic and acute inflammation. Variations in the biochemical status of stroke patients might be acco...

Open access Research Article 10.9734/ajrb/2019/v5i330093

The Effect of Structural Modification on the Blood Brain Barrier Permeation Properties of Allicin

Victor E. Itepu, Ogochukwu J. Umezinwa, Fidelis A. Ilukho, Difa A. Collins & Cosmas Samuel · Asian Journal of Research in Biochemistry · 2019

Allicin is found in nursery onion. Allicin is isolated from garlic (Allium sativum). Nutriceutical allicin is an organice compound gotten from garlic. It is also sourced from onions, and different species in the family Alliaceae. It was first isolated and examined in the research...

Open access Research Article 10.9734/ajrb/2019/v5i330092

Antioxidant, Hypolipidemic and Angiotensin Converting Enzyme Inhibitory Effects of Flavonoid-rich Fraction of Hyphaene thebaica (Doum Palm) Fruits on Fat-fed Obese Wistar Rats

M. A. Abdulazeez, A. Bashir, B. S. Adoyi, A. Z. Mustapha, B. Kurfi, A. Y. Usman & R. K. Bala · Asian Journal of Research in Biochemistry · 2019

Aims: This study investigated the antioxidant, hypolipidemic and angiotensin converting enzyme (ACE) inhibitory effects of flavonoid-rich fraction of H. thebaica on fat-fed obese wistar rats. Study Design: Twenty-five rats were divided into 5 groups of 5 rats each: Control (stand...

Open access Research Article 10.9734/ajrb/2019/v5i330091

Evaluation of Invertase and Amylase Activities of Latic Acid Bacteria Isolated from ‘Pupuru’ (An Indigenous African Fermented Cassava Staple Food)

B. C. Akin-Osanaiye, B. T. Azeez & I. W. Olobayotan · Asian Journal of Research in Biochemistry · 2019

Lactic acid bacteria produce lactic acid as the major end product during sugar fermentation. This study was carried out to isolate lactic acid bacteria (LAB) from pupuru; a staple cassava food. The result of the bacterial count indicated that the count ranges from 3.1 × 104 CFU/g...

Open access Research Article 10.9734/ajrb/2019/v5i330090

The State of Proteins not with Standing, Translational Velocity is Vital for their Function

Ikechukwu Iloh Udema & Abraham Olalere Onigbinde · Asian Journal of Research in Biochemistry · 2019

Background: Targeting of macromolecules by means of translational diffusion for therapeutic reason is generally of interest. But translational velocity that enables directional delivery of any molecule on target is given less attention. Objectives: The objectives of this research...

Open access Research Article 10.9734/ajrb/2019/v5i330089

Amelioration of Monosodium Glutamate-induced Testicular Damage and Infertility in Male Rats by Water Melon and Cantaloupe Seeds Extract and Juices

Shimaa El-Masry & Mai Elsayed · Asian Journal of Research in Biochemistry · 2019

Aims: Monosodium glutamate (MSG) is extensively used as food additive and flavor enhancer, there is a growing concern that this may affect the male reproductive system and fertility. The objective of this study is to investigate the effect of MSG on fertility and testes of mature...

Open access Research Article 10.9734/ajrb/2019/v5i230088

Effect of Oral Intake of Sodium Benzoate on Serum Cholesterol and Proinflammatory Cytokine (Tumor Necrosis Factor Alpha [TNF-α] and Interleukin-6 [IL-6]) Levels in the Heart Tissue of Wistar Rats

Efekemo, Oghenetekevwe, Akaninwor, Joyce Oronne & Essien, Eka Bassey · Asian Journal of Research in Biochemistry · 2019

The in vivo effect of oral administration of varying concentrations (150, 250, 500 mg/kg body wt.) of sodium benzoate (a known preservative in the food, cosmetic and pharmaceutical industry) on serum cholesterol and proinflammatory markers in heart tissue of wistar albino rats we...

Open access Research Article 10.9734/ajrb/2019/v5i230086

Theoretical Insight into Preferential Interaction Issues and Solution Structure, and Contentious Apparent Hydrated Molar Volume of Cosolute

Ikechukwu Iloh Udema & Abraham Olalere Onigbinde · Asian Journal of Research in Biochemistry · 2019

Background: There seems to be a mathematical or a conceptual error in an equation whose substitution into other equations for the determination of an apparent hydrated molar volume (V1) of a cosolute leads to an incorrect answer. Objectives: The objectives are 1) To show theoreti...

Open access Research Article 10.9734/ajrb/2019/v5i230087

Theoretical Investigation into the Change in the Number of Water Molecules in Solvent Inaccessible Region of an Enzyme and Enzyme-substrate Complex

Ikechukwu Iloh Udema & Abraham Olalere Onigbinde · Asian Journal of Research in Biochemistry · 2019

Background: There may be dry enzymes, but water remains indispensable for the catalytic action of enzymes. There is not as much interest in how the presence of a drug such as aspirin and a psychoactive compound such as ethanol may affect the water-mediated role of the enzyme. Obj...

Open access Research Article 10.9734/ajrb/2019/v5i230085

Haematopoietic Potential of Ethanolic Leaf Extract of Talinum triangulare in Wistar Rats

A. I. Airaodion, E. O. Ogbuagu, J. A. Ekenjoku, U. Ogbuagu & E. O. Airaodion · Asian Journal of Research in Biochemistry · 2019

Aim: This study focuses on assessing the haematopoietic potential of ethanolic extract of Talinum triangulare leaves in Wistar rats. Methods: Fresh plants of T. triangulare were purchased from a local market in Orita-Challenge area of Ibadan, Nigeria. They were air dried at room...

Open access Research Article 10.9734/ajrb/2019/v5i230084

Biochemical and Histological Changes Associated with Azo Food Dye (Tartrazine) in Male Albino Rats

Ibioku Elekima, Ogechi Edna Nwachuku, Damion Ukwukwu, Harrison Ugo Nwanjo & Nsirim Nduka · Asian Journal of Research in Biochemistry · 2019

Aim: To study the effect of chronic exposure of tartarzine at ADI doses on some biochemical parameters of male albino rats. Study Design: The design involved chronic study. In the study, the experiment was divided into phase 1, 2, and 3 which lasted for 30, 60 and 90 days respect...

Open access Research Article 10.9734/ajrb/2019/v5i130083

In-vivo Study on Organometallic Compounds as Anticancer Agents

F. Z. Mohammed, Elsherbiny H. Elsayed, Atef E. Abd Elbaky & H. M. Shalaby · Asian Journal of Research in Biochemistry · 2019

This study aims to study the in-vivo anticancer effect of the synthesized copper complexes of 2,3-dihydroxy benzaldehyde thiosemicarbazone (3a,b), followed by evaluating their antioxidant activity.  Materials and methods: A total number of 80 adult female swiss albino mice weighi...

Open access Research Article 10.9734/ajrb/2019/v5i130082

In-vitro Biochemical Studies on Organometallic Compounds as Anticancer Agents

F. Z. Mohammed, Elsherbiny H. Elsayed, Atef E. Abd Elbaky & H. M. Shalaby · Asian Journal of Research in Biochemistry · 2019

This study aims to synthesis of copper complexes of 2,3-dihydroxy benzaldehyde thiosemicarbazone (3a,b), followed by evaluating their in vitro anticancer properties. The prepared compounds have been also evaluated for their ability to induce apoptosis. A total number of 80 adult...

Open access Research Article 10.9734/ajrb/2019/v5i130080

Examination of Conditions for Optimized Decellularized Liver Preparation

Jaeyong Cho, Yukako Fukuda, Nana Shirakigawa & Hiroyuki Ijima · Asian Journal of Research in Biochemistry · 2019

Aims: The main aim of our study was to examine the concentration of surfactant that can cause significant disruption of the resulting decellularized liver structure. Furthermore, it is our goal to determine the suitable solvent that can boost the potential of each surfactant. Met...

Open access Research Article 10.9734/ajrb/2019/v5i130079

Qualitative and Quantitative Phytochemical Screening, Antioxidant and Anti-inflammatory Activities of Acetone Extract of Brassica juncea L. Leaf

Pratima Khandayataray & Meesala Krishna Murthy · Asian Journal of Research in Biochemistry · 2019

Objective: The aim of this study is to evaluate the phytochemical screening; antioxidant and antiinflammatory activity of acetone extract of Brassica juncea (L.) Czern leaf. Methods: Qualitative and quantitative phytochemical screening was conducted by following standard protocol...

Open access Research Article 10.9734/ajrb/2019/v5i130078