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All published articles 499

Inhibitory Activity of β-lactamases by Hydro-Ethanolic Extracts of Harungana madagascariensis, a Plant of the Ivorian Pharmacopoeia

Toty Abalé Anatole, Aka Ayebe Edwige, Guedé Kipré Bertin, Konan K. Fernique, Adrien Jehaes, N. Guessennd, Otokoré D. Albert, M. Dosso & M. Galleni · Asian Journal of Research in Biochemistry · 2020

Infection due to multi-resistant bacteria is a public health concern. Unfortunately, the prospect of developing new antibiotics seem not to be on the horizon. Faced with this impasse, medicinal plants could be an alternative for the development of new molecules. The aim of this s...

Open access Research Article 10.9734/ajrb/2020/v7i430168

Association between TP53 and MDM2 Gene Polymorphisms and Risk of Hepatocellular Carcinoma in Hepatitis C Virus among Egyptian Populations

Ahmed Mohamed Zaky, Shaden Muawia Hanafy, Magdy Mamdouh El- Bordiny & Reham Abdel Haleem Abu El- Wafa · Asian Journal of Research in Biochemistry · 2020

Background: The Murine double minute 2 (MDM2) gene is overexpressed in several human tumors. The oncogenic potential of MDM2 is partially explained by inhibition of the activity of the tumor suppressor protein P53 (negative regulator of the P53 tumor suppressor protein). A single...

Open access Research Article 10.9734/ajrb/2020/v7i430159

Physicochemical and Microbial Evaluation of Selected Residential Borehole Water Samples in Awka, Anambra State, Nigeria

Victor Henry Azubuike Enemor, Precious Ebuka Okeke & Uchechukwu Chibuzo Ogbodo · Asian Journal of Research in Biochemistry · 2020

Water is very important to the existence of humans though could also serve as vehicle for pathogenic organisms and dangerous organic and inorganic matters. The physicochemical and microbial analyses of selected borehole water samples in Awka residential areas were conducted with...

Open access Research Article 10.9734/ajrb/2020/v7i430156

Comparative Study on the Protective Effect of Zinc Nanoparticle and Zinc Supplement on Carbamazepine Induced Reproductive Damage in Male Albino Rats

Auwal Balarabe Bello, Mudassir Lawal & A. Muhammad Hisbullahi · Asian Journal of Research in Biochemistry · 2020

Aim: The aim of this study is to compare the protective effect of zinc nanoparticle and zinc supplement against carbamazepine induced reproductive changes in male Albino rats. Study Design: In this experiment, 60 Male albino rats were used which are divided into six groups of 10...

Open access Research Article 10.9734/ajrb/2020/v7i430157

Electrolyte Concentrations and Liver Enzymes in Car Spray Painters Exposed to Car Spray Paints within Port Harcourt Metropolis, Rivers State, Nigeria

Ibiene Sarah Kalio, O. Onwuli Donatus, Abel Callum Ndubuisi & Obisie-eke Godgift · Asian Journal of Research in Biochemistry · 2020

Aim: To determine the effect of car spray paint on electrolyte concentrations (sodium, potassium, bicarbonate and chloride), Anion gap, Total Protein, Albumin, liver enzymes (Alanine amino transferase and Aspartate amino transferase) of car spray painters. Place of Study:  The st...

Open access Research Article 10.9734/ajrb/2020/v7i430155

Effect of Aqueous Extract of Costus afer Stems on the Liver and Cardiac Enzymes Activities of High Fat Diet Induced Hyperlipidemic Rats

Anyiam C. Chioma, Anyiam. C. Albert, Essien, E. Bassey & Danladi G. Jeremiah · Asian Journal of Research in Biochemistry · 2020

Aim: The present study was carried out on the effect of aqueous extract of Costus afer stems on the liver and cardiac enzymes activities of diet induced hyperlipidemic rats. Methodology: Wistar albino male rats (100-135g) were randomly distributed into 7 groups of 12 rats each. G...

Open access Research Article 10.9734/ajrb/2020/v7i430153

Chemical Profile of the Stem Extract of Costus afer (Bush Cane) from Imo State in Nigeria

Anyiam C. Chioma, Anyiam C. Albert & Anozie J. Kenechukwu · Asian Journal of Research in Biochemistry · 2020

Aim: The aim of the study was to investigate the chemical profile of the stem extract of Costus afer (Bush cane). Methodology: Fresh stems of Costus afer were obtained from Obizi in Ezinihitte Mbaise Local Government Area of Imo State. The stem extract of Costus afer a medicinal...

Open access Research Article 10.9734/ajrb/2020/v7i430154

Determination of the Fermentation Parameters of an Artisanal Beer Based on Wax and Honey in the North of Côte d'Ivoire

Karamoko Detto, Fagbohoun Jean Bedel, Moroh Jean-Luc Aboya, Ouattara Gnénépari Odjo Mahoua & Djè Koffi Marcellin · Asian Journal of Research in Biochemistry · 2020

The aim of this study is to evaluate some microbiological and physicochemical parameters during the production of artisanal beer based on honey and beeswax. Samples were collected at various critical points during the production process. The load of mesophilic aerobic germs and y...

Open access Research Article 10.9734/ajrb/2020/v7i430152

Ocimum gratissimum Capped Sulfur Nanoparticles and Antibacterial Efficacy against Multidrug-Resistant Microbes

Owolabi M. Bankole, Oludare Temitope Osuntokun, Adedapo Adeola & Afolabi Owoeye · Asian Journal of Research in Biochemistry · 2020

This manuscript reports for the first time synthesis of sulfur nanoparticles prepared from thiosulphatepentahydrate ( ) using either oxalic acid alone ( ), or mixture of oxalic acid and aqueous solution of Ocimum gratissimum ( ). The synthesized sulfur nanoparticles were obtained...

Open access Research Article 10.9734/ajrb/2020/v7i430151

The Effect of Norbactin on the Lipid Profile of the Cardiovascular System of Albino Rats

I. M. Uneze, D. N. Azionu & A. S. Ogunbowale · Asian Journal of Research in Biochemistry · 2020

Antibiotics have been reported to produce varied degree of toxicity to different organs and systems. Thus, the present study investigated the effect of Norbactin on the lipid profile of the cardiovascular system of Albino rats. The research was performed on 20 adult male Albino r...

Open access Research Article 10.9734/ajrb/2020/v7i430150

Evaluation of Antioxidant Activity and Polyphenolic Content of Commonly Consumed Egg Plant Varieties and Spinach Varieties in Sri Lanka

H. A. C. O. Hettiarachchi, K. D. P. P. Gunathilake & Sharmila Jayatilake · Asian Journal of Research in Biochemistry · 2020

Aims: To evaluate the antioxidant capacity and the polyphenolic content of commonly consumed egg plant varieties and spinach varieties in Sri Lanka, in order to screen the potential for utilizing them in developing of functional food products. Study Design: Complete randomized de...

Open access Research Article 10.9734/ajrb/2020/v7i430149

Potential Applications of Cereals and Yams as Functional Foods to Reduce the Risk of Chronic Non-Communicable Diseases

N. N. G. Chiranthika, K. D. P. P. Gunathilake & Ananda Chandrasekara · Asian Journal of Research in Biochemistry · 2020

The chronic non-communicable diseases (NCD) are increasing throughout the populations and the burden of diseases is rising globally. Epidemiological evidences supports claim that intake of   foods with certain health benefits and reducing the risk of NCDs are having positive corr...

Open access Research Article 10.9734/ajrb/2020/v7i430148

Comparative Nephrotoxicity and Hepatotoxicity Effects of Kerosene, Gasoline, Liquefied Petroleum Gas and Biomass Fuel Exposure on Male Albino Rats

Ude Tochukwu, Meludu Samuel Chukwuemeka, Dioka Chudi Emmanuel, Chikezie Onyebuchi Desmond, Awalu Chimezie Joseph & Ibekailo Sylvester Nnaemeka · Asian Journal of Research in Biochemistry · 2020

The effects of Kerosene, gasoline, and liquefied petroleum gas and biomass fuel exposure on biomarkers of kidney and liver were investigated in male wistar rats. Fifty adult male wistar rats were randomly assigned to five groups of ten animals each. Rats in group A served as cont...

Open access Research Article 10.9734/ajrb/2020/v7i430147

Changes in Some Biochemical Parameters and Body Weights of Healthy Albino Rats Following Palm-wine Administration

G. S. Haruna, O. B. Nwaikuku, B. A. James, N. Musa & R. Valentine · Asian Journal of Research in Biochemistry · 2020

Aims: To evaluate the effect of palm-wine administration on liver function, antioxidant parameters and body weights in albino rats. Study Design: Randomized block design. Place and Duration of Study: Department of Biochemistry and Molecular Biology Laboratory, Nasarawa State Univ...

Open access Research Article 10.9734/ajrb/2020/v7i430146

Study of the Variation of Some Biochemical Parameters in Rattus norgevicus

Obou Constantin Okou, Djako Sosthène Thierry Akré, Gomé Michel Bleu, Assandé Francis Ehounou & Alain Dit Philippe Bidié · Asian Journal of Research in Biochemistry · 2020

The biochemical assessment in animals is of capital interest to define the diagnosis of many diseases. The variation of biochemical parameters (urea, glycemia, creatinemia, transaminases: GPT and GOT, total cholesterol, HDL-c, LDL-c, triglycerides and total lipids) is an indicato...

Open access Research Article 10.9734/ajrb/2020/v7i430145