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All published articles 421

Investigation on Effect of Stress on Dissolution Stability of Drug Product by Applying Thermal and NonThermal Methods of Analysis

Krishna R. Gupta, Rahul P. Chaudhari, Anita R. Pounikar & Anvesha V. Ganorkar · Asian Journal of Applied Chemistry Research · 2019

Aim: The aim of the research work has to development and validation of dissolution test method for Tapentadol using HPLC method, investigate the effects of stress on dissolution stability by thermal and non-thermal methods. The present research work mainly focused on the evaluati...

Open access Research Article 10.9734/ajacr/2019/v4i1-230103

Determination of Heavy Metals in Selected Tissues and Organs of Cattle from Central Abattoir in Ado-Ekiti, Akure and Owena

Daniel Uwaremhevho Momodu & Adedayo Olamide Oyebanji · Asian Journal of Applied Chemistry Research · 2019

This study was to determine the concentrations of lead (Pb), cadmium (Cd) and zinc (Zn) in the organs (liver, kidney and heart) and tissues (intestine and blood) of slaughtered cattle using spectroscopy method based on comparison with standards. The results obtained for these hea...

Open access Research Article 10.9734/ajacr/2019/v4i1-230102

Solubility Enhancement and Pharmacokinetic Assessment of Chemically Modified Lamotrigine in Rat Blood Plasma by HPLC

Krishna R. Gupta, Ashok R. Gautam, Anvesha V. Ganorkar & Milind J. Umekar · Asian Journal of Applied Chemistry Research · 2019

Aims: • Synthesis/preparation of Lamotrigine (LMN) complexes with β-CD, Caffeine, Nicotinamide, EDTA and • Development of a new reverse phase liquid chromatographic (HPLC) method for the investigation of Lamotrigine in rat plasma after oral administration and pharmacokinetic asse...

Open access Research Article 10.9734/ajacr/2019/v4i1-230101

Varietal Differences in the Oil Composition of the Seed of Two Indigenous Chrysophyllum albidium Species

Bello, Adunola Abosede, Muniru, Oluwasegun Soliu & Igwe, Chima Cartney · Asian Journal of Applied Chemistry Research · 2019

Aim: To investigate the varietal difference in the composition of the oil of two Chryosophyllum albidium species. Study Design: Laboratory experimental design was used. Place and Duration of Study: Chryosophyllum acreanum and Chrysophyllum africana seed species of Chrysophyllum a...

Open access Research Article 10.9734/ajacr/2019/v3i430099

Phytochemical Characterization of Naturalized Sudanese Jatropha curcas Seed Kernels

Nagwa Kamal-Eldin M. Salih & Elhadi M. Yahia · Asian Journal of Applied Chemistry Research · 2019

The objective of this study was to characterize the naturalized Sudanese jatropha (Jatropha curcas L) seed kernel for its proximate composition, minerals, phenolics and fatty acids properties. The results showed 52% crude fat and 24% crude protein in Jatropha seed kernel. Also fa...

Open access Research Article 10.9734/ajacr/2019/v3i430100

Effects of Ultraviolet-B Radiation on the Photosynthetic Pigments and Protein Content of Strawberry

Justin Masih · Asian Journal of Applied Chemistry Research · 2019

The effects of ultraviolet-B (UV-B) radiations were studied on strawberry. The transplanted plants were irradiated with UV-B (280-320 nm) for 30, 60, 90 and 120 minutes on 20th, 40th, and 60th days after transferring. The enhanced UV-B radiation caused a negative effect on photos...

Open access Research Article 10.9734/ajacr/2019/v3i430098

Validated Stability – Indicating Methods for Determination of Sofosbuvir by UPLC and HPTLC in Pure Form and Tablet Dosage Forms

Sawsan A. Abdel-Razeq, Zeinab Adel Nasr & Noha S. Said · Asian Journal of Applied Chemistry Research · 2019

Aims: Two simple and sensitive stability- indicating methods were developed and validated for the quantitative determination of sofosbuvir in presence of its degradation products. Study Design: Ultra high performance liquid chromatography (UPLC), High performance thin layer chrom...

Open access Research Article 10.9734/ajacr/2019/v3i430097

Extraction and Characterization of Oil from Date Palm (Phoenix dactylifera) Seed

J. A. Olowokere, A. I. Onen, M. C. Odineze, I. D. B’aga & E. G. Kefas · Asian Journal of Applied Chemistry Research · 2019

This work focuses on the extraction of oil from date palm seed. Using n-hexane in Soxlet extraction apparatus, standard procedures were followed to determine the oil feed stock yield. Proximate compositions and physicochemical characteristics were carried out. Also, Fourier Trans...

Open access Research Article 10.9734/ajacr/2019/v3i430095

Physicochemical Parameters and Toxic Heavy Metals Concentration in Coffee

Eltigani Osman Musa Omer, Osama Ahmed Labib & Mubashir Zafar · Asian Journal of Applied Chemistry Research · 2019

Background and Objective: Coffee is one of the common drinks in Middle Eastern countries including Saudi Arabia due to its desirable aroma, taste and putative positive physiological functions. The concentration of metals is commonly present in coffee powder. The presence of heavy...

Open access Research Article 10.9734/ajacr/2019/v3i330094

Structural Elucidation, 3D Molecular Modeling and Antibacterial Activity of Ni (II), Co (II), Cu (II) and Mn (II) Complexes Containing Salophen Ligand

Md. Ali Asraf, Md. Mahbubur Rahman, D. C. Kabiraz, Rezaul H. Ansary, Md. Faruk Hossen, Md. Fazlul Haque & C. M. Zakaria · Asian Journal of Applied Chemistry Research · 2019

The salophen ligand and its complexes of Ni(II), Co(II), Cu(II), and Mn(II) are explored in terms of synthesis, conductivity; magnetic measurements, elemental analysis, FT-IR; electronic spectra, and antibacterial activities. The 3D molecular modeling structures of the ligand and...

Open access Research Article 10.9734/ajacr/2019/v3i330093

Synthesis Spectroscopy and Computational Studies of Manganese (II) Complexes Incorporating (N,O)(O,O`) Ligands and Their Biological Activity

Rania Ahmad Abokhater, Salem Eltuhami Ashoor & Suad A. Gadir · Asian Journal of Applied Chemistry Research · 2019

Manganese (II) complexes were synthesized via the reaction equimolar quantity of Manganese(II) chloride-hydrate (MnCl2.6H2O) with Chiral saccharides such {(OH)5(CH2)(C5H5)O} or {(OH)6(CH2)(C5H5)O} and (C9H7NO) as secondary ligands [Mn(C9H7NO){(OH)5(CH2)(C5H5)O}]Cl2 (C1), [Mn(QH){...

Open access Research Article 10.9734/ajacr/2019/v3i330092

Adsorption of Cr6+ Onto Unmodified and Hydrochloric Acid Modified African Nutmeg Pod (Monodora myristica) from Aqueous Solution

F. U. Okwunodulu, H. O. Chukwuemeka-Okorie, N. M. Mgbemena & J. B. I. Kalu · Asian Journal of Applied Chemistry Research · 2019

The removal of Cr6+ from aqueous solution using unmodified and hydrochloric modified African nutmeg pod was studied. The effects of particle size, pH and initial metal ions concentration adsorbed were investigated. The amount of metal ion adsorbed increased as the initial metal i...

Open access Research Article 10.9734/ajacr/2019/v3i330091

Adsorption Performance of Packed Bed Column for the Removal of Lead (II) Using Velvet Tamarind (Dialium indum) Shells

Jibrin Noah Akoji · Asian Journal of Applied Chemistry Research · 2019

The removal of Pb ions by activated carbons prepared from velvet tamarind (Dialium indum) shells was studied to investigate its uptake potentials using column sorption at different operating conditions (flow rates, initial concentrations and bed height). The prepared adsorbent wa...

Open access Research Article 10.9734/ajacr/2019/v3i230089