Skip to content

All published articles 175

Usability of Medicine Package Inserts for Chronic Diseases: A Survey of the Pharmaceutical Market in Jos, Nigeria

B. N. Joseph, U. O. Asiegbu, B. M. Aya, M. N. Nyam, D. M. Umar, N. S. Jimam & M. L. P. Dapar · Journal of Pharmaceutical Research International · 2017

Background: The burden of illness is increasingly tending towards chronic diseases while medication adherence is often unsatisfactory. The patient information leaflet is one model that has the prospect to improve medication adherence. Improving the readability and content based v...

Open access Research Article 10.9734/JPRI/2017/34603

Evaluation of an Undocumented Polyherbal (Faradin®) Used for the Treatment of Sickle Cell Disease in West Africa. Part II: Antibacterial Activity and Synergism

Moji C. Adeyeye, Daniel A. Gbadero, Lawrence O. Farayola, Vicky McKinley, Nikolaos Olalere, Zachary Erlichman, Dami Alabi & Tobi Amosun · Journal of Pharmaceutical Research International · 2017

Aim: This study focused on evaluation of the anti-bacterial effects and synergism of Faradin®), a polyherbal complementary alternative medicine (CAM) and anti-sickling agent. It is used for treatment of sickle cell disease (SCD) and co-morbidities (such as infection and inflammat...

Open access Research Article 10.9734/JPRI/2017/33606

Antimicrobial and Antioxidative Activities in the Stem Extracts of Derris trifoliata, a Mangrove Shrub

Aritra Simlai, Anjali Gangwar, Sarthaki Avinash Ghonge & Amit Roy · Journal of Pharmaceutical Research International · 2017

Aims: An in-depth study on the phytochemical contents, antimicrobial and antioxidative activities of stem tissue of Derris trifoliata Lour. (Fabaceae), a mangrove shrub from Sundarban estuary, India. Methodology: Phytochemical analyses were carried out using established methods f...

Open access Research Article 10.9734/JPRI/2017/34455

Public Knowledge and Awareness about Gout: A Cross-sectional Study in Qatar

Intithar Mohammed M. Alshammari & Md. Ali Mujtaba · Journal of Pharmaceutical Research International · 2017

Background: The prevalence of hyperuricemia and gout had shown an increasing trend all over the world including in developing countries. The patients may receive very little education on the dietary and lifestyle factors associated with gout.  Objective of the Study: Assess knowl...

Open access Research Article 10.9734/JPRI/2017/34375

Prophylactic and Protective Activity of Crude and Methanolic Extract of Punica granatum Peel against Gentamicin Induced Nephrotoxicity

Mobasher Ahmad, Rizwana Wazir, Rukhsana Anwar, Sairah Hafeez Kamran, Afroze Mobasher & Usman Akhtar · Journal of Pharmaceutical Research International · 2017

The aim of the current study was to investigate the nephroprotective effect of Punica granatum peel (pomegranate) against gentamicin induced nephrotoxicity. The crude pomegranate peel (600 mg/kg) and methanolic pomegranate extract (600 mg/kg) for 7 days showed significant (p<0...

Open access Research Article 10.9734/JPRI/2017/34616

A New Emulsifying Agent: Cucumis sativus Linnaeus Mucilage

Oluyemisi Adebowale Bamiro, Tolulope Omolola Ajala & Emmanuella Gbade Adenokun · Journal of Pharmaceutical Research International · 2017

Aim: This study aims at investigating the emulsifying properties of Cucumis sativus mucilage, compare with gelatin and tragacanth with further assessment of their combined effects on the emulsion properties. Place and Duration of Study: Department of Pharmaceutics and Pharmaceuti...

Open access Research Article 10.9734/JPRI/2017/34465

Hypoglycemic and Anti-hyperlipidaemia Effects of Methanolic Extract of Zingiber officinale and its Role in Ameliorating Oxidative Stress in Alloxan-induced Diabetic Rats

Abiodun Olusoji Owoade, Adewale Adetutu & Olubukola Sinbad Olorunnisola · Journal of Pharmaceutical Research International · 2017

This study was designed to examine the hypoglycemic and antioxidant defense by methanolic extract of Zingiber officinale on alloxan induced diabetes in Wistar rats.The preliminary study showed that Z. officinale extract was able to scavenge the 2,2-Diphenyl-1-picrylhydrazyl (DPPH...

Open access Research Article 10.9734/JPRI/2017/34396

Assessment of Antiglycation Effects of Some Plants Used in Hypolipidaemic Formulations or as Spices

H. K. I. Perera, W. K. V. K. Premadasa, W. I. T. Fernando & J. A. V. P. Jayasinghe · Journal of Pharmaceutical Research International · 2017

Aims: Diabetes mellitus is characterized by hyperglycemia, which leads to acceleration of protein glycation. Some glycation products form inter molecular cross-links, contributing to chronic diabetic complications. Determination of protein glycation inhibitory potential of medici...

Open access Research Article 10.9734/JPRI/2017/34049

Pattern of Medication Use among Hypertensives Attending a Specialist Outpatients Clinic in North-Central Nigeria

Umar G. Adamu, Aisha Abdulahi, Fatima K. Ibrahim & Indogesit O. Ibok · Journal of Pharmaceutical Research International · 2017

Background: Hypertension is the commonest cardiovascular risk factor encountered in Cardiology Clinics in Nigeria. The aim of this study was to assess the prescribing pattern of antihypertensive medications and conformity to guidelines by physicians at the Cardiology Clinic of Fe...

Open access Research Article 10.9734/JPRI/2017/33841

In-vitro Studies of Food Interaction with Dihydroartemisinin – Piperaquine Antimalarial Tablet

Sunday O. Awofisayo, Chioma N. Igwe, Nkechinyerem A. Jonathan, Alphonsus I. Francis & Peter D. Ojobor · Journal of Pharmaceutical Research International · 2017

The study assessed molecular interactions between the actives in antimalarial dihydroartemisinin-piperaquine (DP) tablet and food components using Fourier transform infrared spectroscopy (FTIR). Soluble starch, lactose, albumin, sunflower oil and carbonated drinks were pelletized...

Open access Research Article 10.9734/JPRI/2017/28516