The problem of antibiotic resistance is fast becoming a pandemic which has necessitated the need for new drugs discovery. This study was carried out to screen two green algal species- Bryopsis pennata andChaetomorpha anteninna for antibacterial activity against multidrug resistan...
Open access
Research Article10.9734/JPRI/2017/35924
The present review describes the biological activities of synthetic nitro steroids. More than fifty biologically active nitro steroids showed an analeptic, antineoplastic, anesthetic, neuroprotector, immunosuppressant, dermatologic properties, and also show other biological activ...
Open access
Research Article10.9734/JPRI/2017/36196
Nasrin Bahmani, Mohammad Reza Arabestani, Seyed Hamid Hashemi, Abbas Farahani, Reza Mirnejad, Parviz Mohajeri, Manoochehr Karami & Mohammad Yousef Alikhani·Journal of Pharmaceutical Research International·2017
Background: The Brucellosis is recognized as a significant public health problem, with major economic and financial burdens in countries where the disease remains endemic. The disease is one of the most important worldwide zoonosis affecting livestock and humans. The aim of the p...
Open access
Research Article10.9734/JPRI/2017/34911
The aim of this study was to evaluate the effects of fermented soya bean supplements on thyroid profile and serum electrolytes of high fat diet-induced type 2 diabetes in rabbits. Twenty rabbits weighing between 1 kg – 1.5 kg were used for the study. Diabetes was induced by feedi...
Open access
Research Article10.9734/JPRI/2017/35680
Mahrukh Yousaf, Usama Asif, Khurram Aamir, Inaam-ur-rehman ., Sehrish Haider, Afzaal Bashir, Furqan K. Hashmi, Mohamed Azmi Hassali & Zikria Saleem·Journal of Pharmaceutical Research International·2017
Background: Chronic myelogenous leukemia (CML) is potentially curable disease of white blood cells (WBCs) especially granulocytes. Our objective was to evaluate comparative efficacy and safety of two chemotherapy protocols i.e. hyper-CVAD and MEC in patients with CML who were unr...
Open access
Research Article10.9734/JPRI/2017/35631
Aim: Non-adherence with antipsychotics is associated with poor outcomes in patients with schizophrenia. It was anticipated that drop-out from treatment due to non-compliance with oral anti-psychotics could be abated with the use of depot antipsychotics. However previous studies a...
Open access
Research Article10.9734/JPRI/2017/35581
The Batch adsorption experiments were investigated for the adsorption of Amoxicillin (AMO) antibiotic on activated carbon prepared from Azolla filiculoides (ACAF). This study is influenced by different parameters such as ACAF dose, initial AMO dose and reaction time. The experime...
Open access
Research Article10.9734/JPRI/2017/35607
A medicinal plant is any plant in which one or more of its organs contain substances that can be used for therapeutic purpose or which are precursors for the synthesis of useful drugs. In this research, six (6) selected plants were screened for antihemorrhoid activities in mice....
Open access
Research Article10.9734/JPRI/2017/25433
Self-medication with prescription-only-medicine is an important driver of non-rational use of medicines which is highly prevalent in Nigeria, with implications on patients’ health outcomes. Although high accessibility to community pharmacies gives strategic advantage to the Pharm...
Open access
Research Article10.9734/JPRI/2017/34945
Aims: The present study was aimed to evaluate anti-inflammatory and antioxidant potential of methanol root extract of Decalepis hamiltonii. Results: The methanolic extract showed in vitro anti-inflammatory activity inhibition cells 96.1%µg/ml. MTT (3-(4,5-dimethylthiazol-2-yl)-2,...
Open access
Research Article10.9734/JPRI/2017/32070
Background: Dyslipidemia is partly dependent on consumption of edible oils. We set out to determine the atherogenic effects of commonedible oils in Nigeria, in male Wistar rats and to find out if administration of oral kolaviron amelioratedthese effects. Methods: Forty-eight male...
Open access
Research Article10.9734/JPRI/2017/35360
Background: Food additives are subject to certain regulatory requirements, as in some countries, the control is very strict, while in others there is almost no control. Some food supplements can affect existing diseases or interact with some medications, food and beverage, a fact...
Open access
Research Article10.9734/JPRI/2017/35627
Background: Cardiovascular risk factor reduction strategies are more likely to be successful if persons at risk have a good knowledge of the disease and a positive perception of adopting cardio protective behavior .The objectives of this study were to assess the impact of communi...
Open access
Research Article10.9734/JPRI/2017/35064
Aims: This study was aimed at evaluating the potential leukaemia chemotherapeutic activities of various extracts of Kigelia africana stem bark; fruit and leaf by using a benzene-induced model of leukaemia to validate its folkloric use. Evidences from African herbal medicine and t...
Open access
Research Article10.9734/JPRI/2017/34625
Aims: This study investigates the hypoglycemic potential of Archachatina marginata haemolymph and its mechanism in streptozotocin -induced diabetic rats. Study Design: One factor experimental design. Place and Duration of Study: Department of Chemical Sciences, Joseph Ayo Babalol...
Open access
Research Article10.9734/JPRI/2017/33786