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All published articles 1739

Factors Associated with Virological Failure under Dolutegravir-based Therapy in HIV-1 Infected Patients in the Central African Republic (2023–2025)

Laris Michael Dan-Houron Bejendo, Héritier Obed Lango, Clotaire Donatien Rafaï, Christelle Luce Bobossi, Serge Gbazi, Wanh-Ingo Hissein Hereidebona, Bokia Coretha Baguida, Moynam Heredeibona, Boniface Koffi & Ernest Lango-Yaya · Microbiology Research Journal International · 2026

Introduction: HIV‑1 remains a major public health issue, with a prevalence of 3.5% in the Central African Republic. Dolutegravir (DTG)-based regimens are recommended as first-line therapy due to their high efficacy and resistance barrier, yet virological failure persists, influen...

Open access Research Article 10.9734/mrji/2026/v36i51746

Isolation and Antibacterial Activity of Antibiotic-producing Fungi from Selected Soils in Akure, Nigeria

Titilayo Iyanuoluwa Aliu & Muftau Kolawole Oladunmoye · Microbiology Research Journal International · 2026

Background: Soil fungi from diverse and understudied environments such as Akure, Nigeria, represent a promising yet underexplored source of novel antibiotic-producing microorganisms with potential applications against antimicrobial resistance. Aim: The emergence and spread of ant...

Open access Research Article 10.9734/mrji/2026/v36i51744

The Impact of Antibiotic Resistance on the Management of Infectious Diseases: A Systematic Review of Global Trends and Solutions

Khudhur Raheem Obayes, Rafif Aman Mahammed & Hassan Fahim Kamel · Microbiology Research Journal International · 2026

Background: The widespread use of antibiotics in human healthcare, animal husbandry, and agricultural practices constitutes a major source of selective pressure that facilitates the emergence, persistence, and proliferation of antibiotic-resistant strains. Continuous exposure to...

Open access Research Article 10.9734/mrji/2026/v36i51745

Molecular Identification of Antibiotics Resistance Bacteria Isolated from Untreated Water Sources Fed into Sokoto Water Board for Municipal Consumption, Sokoto State, Nigeria

Hussaini Salisu, Mudassir Iliyasu, Mudassiru Salihu, Bahira Bello Yabo, Jafar Usman, Abdullahi Yasmin, Mudassir Abubakar Baba & Murtala Hamidu · Microbiology Research Journal International · 2026

Water quality is essential for life, but contamination from heavy metals and antibiotic-resistant microorganisms in aquatic environments poses serious risks to human health and ecosystems. This study evaluated the microbiological quality of untreated water sources fed into in Sok...

Open access Research Article 10.9734/mrji/2026/v36i51743

Phenotypic Characterization of Mycotoxigenic Fungi Isolated from Palm Oil Sold Within Bauchi Metropolis, Nigeria

H. M. Ghazali, U. S. Haruna, A. Salisu, P. Moses, A. J. Na’Allah, A. Ahmad, B. I Olawale, H. Tahir, Z. M. Kabeer & M. Y. Iliyasu · Microbiology Research Journal International · 2026

Background and Aim: Palm oil is widely consumed in Nigeria, but poor handling, storage, and marketing conditions predispose it to fungal contamination and mycotoxin production, posing public health risks. This study aimed to phenotypically characterize mycotoxigenic fungi isolate...

Open access Research Article 10.9734/mrji/2026/v36i51742

Essential Oils of Melaleuca leucadendra and Melaleuca quinquenervia: Chemical Composition and Efficacy Level in Controlling in Vitro Isolates of Potentially Aflatoxin-Producing Aspergillus flavus

Safietou Sabaly, Mouhamed Lamine Cisse, Abdoulaye Faye, Abdoulaye Ndiaye, Aboubacry Kane, Yoro Tine & Saliou Ngom · Microbiology Research Journal International · 2026

Among the mycotoxins of health and economic importance, aflatoxins hold a prominent place. This study aims to determine the chemical composition of the essential oils of Melaleuca leucadendra and Melaleuca quinquenervia, and to evaluate their effectiveness in the in vitro control...

Open access Research Article 10.9734/mrji/2026/v36i51741

Molecular Detection and Analysis of Carbapenemase Encoding Genes (NDM & OXA-48) in Clinical Strains of Klebsiella pneumoniae Isolated from Urine Samples

Pragati Singh, Usha Verma & Juhi Chaudhary · Microbiology Research Journal International · 2026

Carbapenem resistance among uropathogens is a growing public health concern due to the spread of carbapenemase genes such as blaNDM and blaOXA-48, which reduce the effectiveness of last-line β-lactam antibiotics. This study investigated the presence of these genes in bacteria iso...

Open access Research Article 10.9734/mrji/2026/v36i51740

Genomic and Evolutionary Dynamic Surveillance of Mpox Diagnosed at the National Laboratory of Clinical Biology of Public Health in the Central African Republic

Hériter Obed Lango, Romaric Lebon Bondom, Laris Michal Dan Houron Benjendo, Collins Tanuis, Eddy Kinganda Lusamaki, Benjamin Biallé, Héritier Jephté Lango, Serge Gbazi, Elvis Mapoka, Simon Pounguiza, Christelle Luce Bobossi, Stéphanie Judith N’Yetobouko, Coretha. B. D Baguida-Bokia, Moynam Ekte Heredeibona, Henri Saint-Claver Djiemer, Boniface Koffi, Mathieu Groussin, Ernest Lango-Yaya & Wilfried Sylvain Nambei · Microbiology Research Journal International · 2026

The recent MPXV epidemic in Africa revealed significant viral diversity and complex transmission dynamics, warranting a sub-regional genomic study. We analysed 1,630 high-quality MPXV clade Ia genomes from seven Central African countries, revealing the complex and concurrent circ...

Open access Research Article 10.9734/mrji/2026/v36i51739

Minimally Age-Dependent Gut Microbial Signatures in Pancreatic Neoplasia Identified by qPCR Targeting the but Gene

Tadashi Fujii, Eizaburo Ohno, Yoshiki Hirooka & Takumi Tochio · Microbiology Research Journal International · 2026

Background & Aims: Age-related variation in the gut microbiota complicates biomarker discovery for pancreatic cancer. This study aimed to identify microbial taxa with minimal age dependence that are associated with pancreatic neoplasia and to develop a practical quantitative...

Open access Research Article 10.9734/mrji/2026/v36i41737

Prevalence, Risk Factors and Susceptibility for Notifiable Typhoid and Paratyphoid among Patients Attending the Regional Hospital Bamenda, Cameroon

Gerald Ngo Teke, Ngaibe Charlene Limnyuy & Tashie Evangeline Ngwanguong · Microbiology Research Journal International · 2026

Background: Typhoid and paratyphoid are global diseases among the major public health concerns in developing countries, including Cameroon, especially in areas where tap water is not widely available. Understanding the burden and risk factors contributing to the transmission and...

Open access Research Article 10.9734/mrji/2026/v36i51738

Impact of Empirical Antibiotic Therapy on the Carriage and Acquisition of Multidrug-Resistant Enterobacteriaceae in Paeditric Department of Sylvanus Olympio Teaching Hospital, Lomé, Togo

Fiali Ayawa Lack, Koffi Mawuse Guédénon, Mawussi Godonou, Novissi Tsogbale, Rogatien Comlan Atoun, Anoumou Yaotsè Dagnra & Mounerou Salou · Microbiology Research Journal International · 2026

Background: Antibiotic resistance in Enterobacteriaceae is a major global threat, particularly in hospitalized children, where it leads to difficult-to-treat infections and prolonged hospital stays. The gastrointestinal tract serves as a key reservoir for transmission, and limite...

Open access Research Article 10.9734/mrji/2026/v36i41736

Antagonistic Activities of Indigenous Lactic Acid Bacteria Isolated from Fermenting Cashew Apples against the Fungal Complex Causing Post-harvest Carrot (Daucus carota L.) Rot in the Department of Daloa, Center-West, Côte d'Ivoire

Laure Doriane Kouassi, Ousmane Fofana, Estelle Adjoua Konan, Toualy Serge Thibaut Ouina & Bi Rosin Don Rodrigue Voko · Microbiology Research Journal International · 2026

Carrots are an essential food crop in Côte d'Ivoire; however, their shelf life is limited by dehydration and fungal decay. Given the health risks associated with chemical preservatives, identifying biological conservation alternatives is crucial. This study evaluated the capacity...

Open access Research Article 10.9734/mrji/2026/v36i41734

Antimicrobial Efficacy of Silver Nanoparticles (AgNPs) in Combination with Hand Sanitizer against Foodborne and Spoilage Bacteria

Neha Chatterjee, Akshada Shankar Ganesh, Arjya Roy & Aniesha Owlak · Microbiology Research Journal International · 2026

Silver nanoparticles (AgNPs) are recognized for their broad-spectrum antimicrobial properties against foodborne bacteria, including E. coli, S. aureus, and B. subtilis. This study investigated whether AgNPs at varying concentrations (0.10%, 0.25%, 0.50%) could enhance the antimic...

Open access Research Article 10.9734/mrji/2026/v36i41735

Bacteriological Profile and Antibiotic Resistance of Uropathogens Bacteria in Pregnant Women in Conakry, Guinea

Abdoulaye Makanera, Taliby Dos Camara, Fatoumata Koné,  Moise Koi Koivogui, Mariam Condé, Oumar Souaré, Bintou Konaté, Alpha Oumar Barry & Kounady Fatoumata Camara · Microbiology Research Journal International · 2026

Introduction: Urinary tract infections (UTIs) represent one of the most common bacterial infections worldwide, particularly affecting pregnant women. Objective:  The aim of the present study was to describe the bacteriological profile and antibiotic susceptibility patterns of uro...

Open access Research Article 10.9734/mrji/2026/v36i41733

Multidrug-Resistant Escherichia coli in Commercial Grasscutter (Thryonomys swinderianus) Farms: Prevalence and Association with Bio-Preservation Practices in Togo

Essozimna Sondou, Rogatien Comlan Atoun, Akoélé Siliadin, Amegnona Agbonon, Esther Abla Ahouefa Konou, Didier Koumavi Ekouevi, Anoumou Claver Dagnra & Mounerou Salou · Microbiology Research Journal International · 2026

Introduction: In Togo, limited data exist on the implementation of biosecurity and bio-preservation practices in animal production systems, particularly in grasscutter (Thryonomys swinderianus) farming. This study aimed to describe the level of intestinal microbiota contamination...

Open access Research Article 10.9734/mrji/2026/v36i41729