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Pharmacochemical Evolution of Carbapenems and Structural Analogues

Songuigama Coulibaly, Jean-Paul D.U. N'guessan, Apleheni E.M. Adouko, Jean-Fabrice K. Koffi, Lise A Koffi & Mahama Ouattara · Chemical Science International Journal · 2025

Carbapenems are a major class of antibiotics with a β-lactam nucleus that are distinguished by their effectiveness against many resistant pathogens. The discovery of Thienamycin, from Streptomyces cattleya, was the starting point for these antibiotics that revolutionized the trea...

Open access Research Article 10.9734/CSJI/2025/v34i1944

Elemental Analysis and Proximate Composition of Guiera senegalensis Leaves from West Kordofan, Sudan

Ahmed Abed Elmalik, Fath Elrahman Ahmed & Abed Elsalam A. · Chemical Science International Journal · 2024

This study investigates the proximate composition and elemental contents of Guiera senegalensis leaves collected from West Kordofan, Sudan, and the leaf powder was prepared and analyzed using inductivity-coupled plasma \ Optical Emission Spectrometry to determine the concentratio...

Open access Research Article 10.9734/CSJI/2024/v33i6945

Synthesis, and Characterization of Metal Transition Complexes Derived from the Schiff Base Ligand N,N'-Bis (5-bromosalicylidene)-Propane-1,2-Diamine (H2L)

Mbossé Ndiaye Guèye, Mariama Thiam, Pedro Henrique de Oliveira Santiago, Ngoné Diouf, Ibrahima Elhadji Thiam, Ousmane Diouf, Javier Ellena, Abdou Salam Sall & Mohamed Gaye · Chemical Science International Journal · 2024

Five new transition metal complexes [Mn(L)(Cl)] (1), [Fe(L)(Cl)] (2), [Co(L)(H2O)2] (3),  [Ni(L)(H2O)] (4) and [Cu(L)] (5), are synthesized from the Schiff base ligand N,N'-Bis(5-bromosalicylidene)-propane-1,2-diamine (H2L) which derived from the condensation of 5-bromosalicylald...

Open access Research Article 10.9734/CSJI/2024/v33i6942

Elimination of Sulfate Ions in Water by Addition of an Acidified Calcium Carbonate Suspension

Attika SABIOU MAHAMAN, Mamane Imrana CHAIBOU OUSMANE, Abdou Salam MANZOLA, Zeinabou Mouhamadou & ABDOUL BARI IDI Awali · Chemical Science International Journal · 2024

In humans, long-term consumption of water with sulfate levels between 500–750 mg/l can lead to laxative effects, catharsis, dehydration, and irritation of the gastrointestinal tract. As a result, sulfate removal has been widely studied by researchers globally. This study focuses...

Open access Research Article 10.9734/CSJI/2024/v33i6941

Varied Analysis of Acid Dissociation Constants by Cyclic Voltammetry and UV-Visible to Determine the Aqueous Solubility of a New Diisopropylammonium Phenylsulfonate Molecule

Dame Seye, Déthié Faye, Momath Lo, Cheikh A. B. Diop, Mamadou Dieng, Cheikh A. K. Diop & Modou Fall · Chemical Science International Journal · 2024

The determination of dissociation constant, solubility and thermodynamic parameters are very important physico-chemical parameters in substances and their knowledge is of fundamental importance for the validation of a pharmaceutical ingredient target. The determination of these p...

Open access Research Article 10.9734/CSJI/2024/v33i6940

QSAR, Pharmacophore and Molecular Docking Studies for the Design of Novel Arylamide-derived Inhibitors of Mycobacterium tuberculosis

Adama Niaré, Abadê Ange-Boris N’guessan, Akassa Marius Bernard Djako, Georges Stephane Dembele, Mamadou Guy-Richard Koné & Yaya Yéo · Chemical Science International Journal · 2024

Tuberculosis is an infectious disease caused by the bacterium Mycobacterium tuberculosis. It remains a significant public health challenge worldwide. In 2022, approximately 10.6 million people were diagnosed with tuberculosis, and 1.3 million individuals lost their lives to the d...

Open access Research Article 10.9734/CSJI/2024/v33i6939

Photochemical Removal of Methylene Blue from Aqueous Solutions Using Surface Morphology Techniques

Meledje Djedjess Essoh Jules-César, Djamatché Paul Valery Akesse, Kouadio David Léonce, Yapi Yapo Hermann Aristide, Zran Yvan, Gouli Bi Irié Marc & TROKOUREY Albert · Chemical Science International Journal · 2024

Methylene blue (MB) is a synthetic dye widely used in textile industries. This work describes the application of solar radiation to direct degradation by photolysis of methylene blue in aqueous solution. Experiments were conducted at room temperature to study the effects of expos...

Open access Research Article 10.9734/CSJI/2024/v33i6937

Optimized Photocatalytic Degradation of Methylene Blue Using Titaniferous Sand/ZnO Composite: A Sustainable Approach to Wastewater Treatment

El Hadji Moussa Diop, Maryam Khadim MBACKE, Mamadou Faye & Babacar DIOUF · Chemical Science International Journal · 2024

This study explores a novel approach to enhancing photocatalytic efficiency by utilizing an industrial residue, titaniferous sand, in combination with ZnO. The purifying efficiency of this semiconductor mixture was studied for the removal of methylene blue in a fixed-bed reactor....

Open access Research Article 10.9734/CSJI/2024/v33i6936

Synthesis, Characterization and X-Ray Structure of Mononuclear Cu(II) Complex of the Schiff Base 2,2’- [1,1’-(Ethane-1,2-Diyl) Bis (Nitriloethylidyne)]Diphenol

Gorgui Awa Seck, Mamour Sarr, Marc Lenertz, Emilie Delahaye, Pierre Rabu, Mayoro Diop, Farba Bouyagui Tamboura & Mohamed Lamine Gaye · Chemical Science International Journal · 2024

The reactions of the Schiff base 2,2’-[1,1’-(ethane-1,2-diyl)bis(nitriloethylidyne)]diphenol (H2L), which was synthesised by condensation of 2-hydroxyacetophenone and ethylenediamine in the 2:1 ratio, with acetate copper (II) Salt, afforded a new mononuclear complex formulated as...

Open access Research Article 10.9734/CSJI/2024/v33i6935

Development of ZrO2-Coated SPME Fibers for Detecting Benzotriazole Ultraviolet Filters in Water Samples

Xiaoyan Shen & Huiju Wang · Chemical Science International Journal · 2024

In this study, the zirconium dioxide nanoparticles (ZrO2NPs) were coated on the surface of stainless steel (SS) by cyclic voltammetry (CV) as solid phase microextraction fiber coating for detection of the benzotriazole ultraviolet filters (BUvFs) in different real water samples....

Open access Research Article 10.9734/CSJI/2024/v33i6934

Phytochemical Profile and Antibacterial Activity of Solid Residues from Hydrodistillation of Cymbopogon nardus from Burkina Faso

Assétou Sankara, Jean Claude W. Ouédraogo, Mamourou Zerbo, Bassalia Ouattara & Yvonne L. Bonzi-Coulibaly · Chemical Science International Journal · 2024

Hydrodistillation of aromatic plants is an extraction process that provides essential oils and also generates unexploited solid and liquid residues. The present study focussed on knowledge on the phytochemical profile and antibacterial potential of the solid residue resulting fro...

Open access Research Article 10.9734/CSJI/2024/v33i6930

Removal of Residual Phosphorus and Nitrates from Sewage Treatment Plants by a Fine Sand Filter

Kouadio Brou Albert, Meledje Djedjess Essoh Jules-César, Yobouet Yao Augustin, Zran Vanh Eric Simon & TROKOUREY Albert · Chemical Science International Journal · 2024

Studies on eutrophication affirm that phosphorus is the limiting factor on which action must be taken to avoid the production of algal biomass and the appearance of green tides in waterways. A concentration of 1 mg/L of phosphorus in a body of water is sufficient to trigger eutro...

Open access Research Article 10.9734/CSJI/2024/v33i6931

Mathematical Modelling of the Drying Kinetics of Clupea harengus from Congo

Arnaud W. G Tamba Sompila, Nadia P. G. Pambou-Tobi, Madiélé Mabika Aimé Bertrand, Michel Elenga, Reyes H. Gampoula, Gloire H. Louya Banzouzi, Haïshat Souleymane Mahoumi & Sylvia Petronille Ntsossani · Chemical Science International Journal · 2024

Modeling means finding a mathematical relationship between coordinates. focused on the kinetics of herring fish. Herring fish, known in the Congo vernacular as “makouala”, is available in large quantities in the country. Its consumption and exploitation constitute an important so...

Open access Research Article 10.9734/CSJI/2024/v33i6932

Synthesis of New Dihydropyrimidine-2-Thione Derivatives and Their Antibacterial Screening

Ambeu-Loko N’ta Christelle Mélissa, Camara Mahama, Coulibaly Souleymane, Ouattara Logopho Hyacinthe, Stéphanie Kra, Gnaly Prisca, Fante Bamba, Kassi Amian Brise Benjamin, Cédric Logé & Jean-Michel Robert · Chemical Science International Journal · 2024

In this work, we reported the synthesis of new dihydropyrimidine-2-thione derivatives 5a-h. The reaction intermediates of these derivatives are chalcones or 1,3-diarylprop-2-en-1-one derivatives 3a-h, synthesized from acetophenone and various aldehydes which have not yet been use...

Open access Research Article 10.9734/CSJI/2024/v33i6933