B cells have an important role in immune system due to their role in positive and negative regulation of immune response. As positive regulators, B cells can give rise to antibody-producing plasma cells, are critical cellular adjuvants that facilitate optimal CD4+ T-cell activati...
Open access
Research Article10.9734/JALSI/2015/17458
Aim: To evaluate the larvicidal efficacy and identify the active phytochemical of Ocimum gratissimum n-hexane leaf extract on mosquito larvae. Study Design: Reflux extraction, standard qualitative phytochemical tests, Column and Thin layer chromatographic methods and GC- MS analy...
Open access
Research Article10.9734/JALSI/2015/17099
Aim: To investigate the antidiabetic properties of seed oil of Moringa oleifera Lam. Extracted with petroleum ether and dichloromethane and compared with glibenclimide. Study Design: Experimental study design was adopted. Methodology: The 2.0 ml/kg body weight (kg.bw) of the oil,...
Open access
Research Article10.9734/JALSI/2015/16048
Aim: To determine the effect of tea polyphenols and methotrexate on viability and reactive oxygen species (ROS) in a naturally resistant breast cancer cell line MDA-MB-231. Methodology: MDA-MB-231 cells were selected as a model for methotrexate resistant breast cancer. Drug tests...
Open access
Research Article10.9734/JALSI/2015/14142
Aim of Study: To optimize a triplex real-time PCR assay developed elsewhere and to evaluate the performance characteristics of two different multi-channel real-time PCR systems on the newly optimized assay. Methodology: A triplex real-time PCR assay developed for three key genes...
Open access
Research Article10.9734/JALSI/2015/12939
Aims: The primary aim of this study was to evaluate the effect of halofuginone on serum of thiobarbituric acid reactive substances (TBARS) and plasma testosterone, and 13,14-dihydro-15-keto-prostaglandinF2α (PGM) levels in male yearling sheep. It was also evaluated the effects of...
Open access
Research Article10.9734/JALSI/2015/16475
The present study was aimed at evaluating the effect of Sesamum indicum (linn) seeds supplemented diets on blood glucose, lipid profiles and serum enzymes in alloxan induced diabetic rats. Forty male albino Wistar rats were divided into two broad groups based on diet supplementat...
Open access
Research Article10.9734/JALSI/2015/15941
The pipoid frogs belonging to the super family Pipoidea of the order Anura are mostly represented in fossil forms with only limited data from the extant materials. Pipidae is a pipoid family of the clawed, tongueless and toothless aquatic frogs with pertinent morphological charac...
Open access
Research Article10.9734/JALSI/2015/15016
Background: The persistence of toxic herbicides in water and soil has been considered to be potential environmental concern. As atrazine is still used in Nigeria as a major herbicide, a continuous search for atrazine degrading microorganisms is required. Objectives: The effects o...
Open access
Research Article10.9734/JALSI/2015/14345
Aims: The study was carried out to evaluate the effect of gender and height on blood pressure and heart rate of young adults. Study Design: A cross-sectional study. Place and Duration of Study: Ninety one (91) medical students aged 18-30 years at University of Abuja, Nigeria were...
Open access
Research Article10.9734/JALSI/2015/14387
The review covers different aspects of structural and functional features of magnetic nanoparticles. Especially those which are associated with their interaction with cells and cause development of oxidative stress, apoptosis disruption of DNA structure and cytoskeleton, changes...
Open access
Research Article10.9734/JALSI/2015/15179
Aim: The aim of this study was to determine some biomarkers of immunology and hematology in streptozotocin- induced diabetic wistar rats consuming Gongronema latifolium leaf diets in order to evaluate the involvement of the diet in the management of immunological and hematologica...
Open access
Research Article10.9734/JALSI/2015/14268
Aims: This study was carried out to evaluate the antimicrobial activity of methanol extract of fecal droppings of common house lizard/gecko (Hemidactylus frenatus). Methodology: The antimicrobial activity of the methanol extract of fecal droppings of common house lizard/gecko was...
Open access
Research Article10.9734/JALSI/2015/13059
Aim: The aim of this research was to ascertain the quality of the honeydew honey harvested with wood smoke. Methodology: The sample was stored in a container underlined with aluminium foil and then covered with a cork and kept for subsequent analyses. The sample was analyzed for...
Open access
Research Article10.9734/JALSI/2015/13808
Background: Organochlorine pesticides (OCPs) are compounds that have been widely used in agriculture to control pests and also in the field of public health to control of paludism dissemination and other vectors. Currently, they are banned in most countries because they constitut...
Open access
Research Article10.9734/JALSI/2015/13444